Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil)

Department of Basic Sciences in Health, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Avenida Fernando Correa da Costa, No. 2367, University Campus, 78060-900 Cuiabá, MT, Brazil.
Evidence-based Complementary and Alternative Medicine (Impact Factor: 1.88). 02/2012; 2012(2):272749. DOI: 10.1155/2012/272749
Source: PubMed


Traditional knowledge is an important source of obtaining new phytotherapeutic agents. Ethnobotanical survey of medicinal plants was conducted in Nossa Senhora Aparecida do Chumbo District (NSACD), located in Poconé, Mato Grosso, Brazil using semi-structured questionnaires and interviews. 376 species of medicinal plants belonging to 285 genera and 102 families were cited. Fabaceae (10.2%), Asteraceae (7.82%) and Lamaceae (4.89%) families are of greater importance. Species with the greater relative importance were Himatanthus obovatus (1.87), Hibiscus sabdariffa (1.87), Solidago microglossa (1.80), Strychnos pseudoquina (1.73) and Dorstenia brasiliensis, Scoparia dulcis L., and Luehea divaricata (1.50). The informant consensus factor (ICF) ranged from 0.13 to 0.78 encompassing 18 disease categories,of which 15 had ICF greater than 0.50, with a predominance of disease categories related to injuries, poisoning and certain other consequences of external causes (ICF  =  0.78) having 65 species cited while 20 species were cited for mental and behavioral disorders (ICF  =  0.77). The results show that knowledge about medicinal plants is evenly distributed among the population of NSACD. This population possesses medicinal plants for most disease categories, with the highest concordance for prenatal, mental/behavioral and respiratory problems.

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    • "The plant name was checked with, on the 14th of August 2014. The plant collection was done based on an earlier ethnopharmacological study (Bieski et al., 2012). In order to access the traditional knowledge associated with genetic resources for research purposes from the traditional communities, an ethical clearance (approval no. "
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    ABSTRACT: Ethnopharmacological relevance: Helicteres sacarolha, popularly known in Brazil as 'rosquinha', 'sacarolhas', 'semente-de-macaco', is widely distributed in different phytogeographic zones in Brazil. Preparations from its roots and leaves are employed in popular Brazilian medicine in the treatments of ailments such as peptic ulcer, hypertension among others. Cytotoxicity, acute oral and subchronic toxicity of the hydroethanolic extract of Helicteres sacrolha was investigated as well as the classes of phytochemical present in the extract. Materials and methods: Hydroethanolic (70%) extract of Helicteres sacarolha (HEHs) was prepared by maceration. Potential cytotoxicity was evaluated in CHO-k1 cells. Acute administration of HEHs was done in mice as a single dose up to 5000mg/kg and subchronic oral toxicity study for 30 days in Wistar rats at daily oral doses of 0, 250 and 750mg/kg b.w. Clinical observations and toxicological related parameters were determined every 6 days. Blood was collected for biochemical and hematological analyses, while histological examinations were performed on selected organs. Selected secondary metabolites detected were quantified by UV-spectrophotometry and high performance liquid chromatography (HPLC). Results: The extract was non-cytotoxic to CHO-k1 cells. In acute oral toxicity, there was no mortality or clinical alterations in the female mice, at all doses, except for the transient diarrhea observed at 5000mg/kg acute. Doses up to 2000mg/kg caused no mortality or treatment-related clinical manifestations in the male mice, but treatment-related alterations were however observed at 4000mg/kg, with mortalities recorded at 5000mg/kg. During the subchronic oral toxicity study, no mortality or treatment-related clinical signs were observed. Differences in relative organ weight, hematological parameters and histopathology observations between the treated and the control groups were considered not to be treatment-related. Spectrophotometric analysis revealed the presence of relatively high content of phenolics and flavonoids in HEHs. HPLC analysis confirmed the presence of the quantified compounds and demonstrated the presence of ellagic acid, morin and naringin. Conclusion: Our results confirmed that HEHs have a broad safety margin for therapeutic use.
    Journal of Ethnopharmacology 09/2014; 157. DOI:10.1016/j.jep.2014.09.013 · 3.00 Impact Factor
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    • "ex Hayne (Fabaceae) is a medicinal plant found in the Brazilian savannah and popularly known as “Jatobá-do-cerrado” [7]. Its stem barks are widely used in infusion or decoction to treat stomach pain, asthma, bronchitis, ulcers, diarrhea, flu, and cough [8–10]. "
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    ABSTRACT: The aim of this study was to investigate the antimicrobial activity of different extracts and fractions obtained from Hymenaea stigonocarpa stem barks. The cyclohexanic, ethyl acetate, ethanol, aqueous, and hydroalcoholic extracts were obtained by maceration. The hydroalcoholic extract was partitioned, which resulted in the ethyl acetate and aqueous fractions. All extracts and fractions were subjected to phytochemical screening and evaluation of total phenol and tannin contents. An HPLC-DAD and ultrastructural alterations analysis were performed. Terpenes and coumarins were detected in the cyclohexanic extract. Flavonoids and condensed tannins were present in the other extracts and fractions. The extracts with the highest contents of tannins, ethanol (EE), hydroalcoholic (HE), and aqueous fraction (AF) showed also the highest antimicrobial activity. The MIC values ranged from 64 to 526 µg/mL. The chromatographic fingerprints suggest the presence of astilbin and other flavonoids in EE and HE. Presence of the thick cell wall, undulating outer layer, abnormal septa, and leakage of the cytoplasmic contents and absence of cell wall and cell lyses were the main alterations observed on Staphylococcus aureus ATCC 33591 after treatment with the Hymenaea stigonocarpa hydroalcoholic extract. The presence of phenolic compounds like flavonoids and tannins is possibly the reason for the antimicrobial activity.
    The Scientific World Journal 12/2013; 2013(5):862763. DOI:10.1155/2013/862763 · 1.73 Impact Factor
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    • "In contrast with community-based ethnobotanical surveys , where the investigated resources are directly accessible in loco [8] [9] [10] [11], research at markets and fairs is much more complex, as a significant proportion of the plant products offered to the consumers are uncharacteristic or lack the elements required for accurate taxonomic identification "
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    Evidence-based Complementary and Alternative Medicine 10/2013; 2013(2-3):102714. DOI:10.1155/2013/102714 · 1.88 Impact Factor
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