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Mitigation of Inflammation with Foods

USDA Arkansas Children's Nutrition Center , Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 15 Children's Way, Little Rock, Arkansas 72202, United States.
Journal of Agricultural and Food Chemistry (Impact Factor: 3.11). 04/2012; 60(27). DOI: 10.1021/jf3007008
Source: PubMed

ABSTRACT Constant overproduction of pro-inflammatory molecules leads to chronic inflammation. Unlike acute inflammation, which is essential for healing, chronic inflammation can delay healing and, if left unchecked, contribute to a host of diseases. There is growing evidence that some dietary factors can play important roles in maintaining health and even reversing the progression of chronic diseases, with anti-inflammatory effects as important underlying mechanism. Such findings add to the body of evidence that certain dietary components, including polyphenols and other types of compounds, found in various dietary factors including fruits, berries, vegetables, nuts, whole grains, and foods of marine origin, can play an important role in attenuating and mitigating chronic pro-inflammatory processes associated with chronic diseases.

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Available from: Alexander G Schauss, Aug 29, 2015
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    • "In Fact Sheet No. 317 (September 2012), the World Health Organization (WHO) states that globally, more premature deaths are attributed to Cardiovascular Diseases (CVDs) than to any other cause. Diabetes, hypertension, and other non-communicable pathologies are known to be high risk factors for CVDs, and obesity plays a significant role in all of them (Codoñer-Franch et al. 2011, Raiko et al. 2012, Wu and Schauss 2012). Obesity is associated with a persistent systemic lowgrade state of inflammation as a result of the deterioration of metabolic homeostasis, such as occurs when digestive activities are consistently overwhelmed (Bakker et al. 2010, Monteiro and Azevedo 2010). "
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    • "In vitro and in vivo studies have shown that dietary components can protect against inflammation [8]. Plant-derived phytochemicals, such as specific polyphenols, have been shown to inhibit cell signaling processes that are involved in the inflammatory response, thus attenuating synthesis of proinflammatory cytokines and cell adhesion molecules [9]. "
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