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Available from: Gustavo P. Amarante-Mendes, Aug 12, 2015
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    • "The morphologic changes in cells after treatment with compound 5f were assessed by fluorescence microscopy after staining with AO/EB. Live cells exhibit normal green nuclei early apoptotic cells show bright green nuclei with condensed or fragmented chromatin; late apoptotic cells display condensed and fragmented orange chromatin, whereas necrotic cells showed structurally normal orange nucleus (Kasibhatla et al., 2006; Sukardiman et al., 2007). The cytotoxicity of compound 5f at 5 lM against PC3, Bcap-37, and MGC-803 cells for 12 h was detected by AO/ EB staining, with HCPT used as a positive control at 10 lM for 12 h. "
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