A serological investigation of bluetongue virus in cattle of south-east Iran.

Department of Clinical Studies, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran. .
Veterinaria italiana (Impact Factor: 0.68). 01/2012; 48(1):41-4.
Source: PubMed

ABSTRACT The aim of this study was to describe the seroprevalence rate of bluetongue virus (BTV) in cattle herds in south-east Iran. A total of 188 serum samples were collected from 20 cattle herds (10 animals in each herd) that were randomly selected between 2009 and 2010. A total of 12 samples were eliminated because of inadequacy. Antibodies to BTV in sera were detected using a commercial competitive enzyme-linked immunosorbent assay (c-ELISA). The seroprevalence rate in cattle was 2.13%. All sampled animals were female and age did not affect the prevalence of infection.

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Background The present study describes the pathologic changes in the brain and the spinal cord of aborted, stillbirth and deformities of newborn lambs infected with viral agents.Methods From February 2012 to March 2013, a total of 650 aborted fetuses from 793 pregnant ewes were studied from 8 flocks at different areas in the Mazandaran province in the north of Iran. And randomly, systematic necropsy was performed to collect tissues, and all gross abnormalities were recorded at necropsy by the pathologist .Nevertheless, we conducted a limited number of necropsies for aborted fetuses.ResultsIn the most cases, arthrogryposis was the most common musculoskeletal defects and at necropsy, malformations of the brain included hydranencephaly, porencephaly, hydrocephalus and cerebellar hypoplasia, mainly in the brain stem and gray and white matter of the brain and cerebellum were observed. Histopathologic lesions included chronic multifocal lymphoplasmacytic encephalitis(nonsuppurative) with extensive perivascular cuffing in some cases, formation of glial nodules mainly in the mesencephalon, thalamus, hippocampus, pons and medulla oblongata in the brain of aborted fetuses, and neuronal degeneration, necrosis and central chromatolysis mainly in the cortex and subcortical of the brain and brain stem regions of them. Furthermore, microscopic lesions are mostly linked to a neurodegenerative and necrotic cell death process in the gray matter of ventral horn of the spinal cord. Briefly, histopathologic findings in the brain and spinal cord included hyperemia, hemorrhage, non-suppurative encephalitis, mononuclear perivascular cuffing, multifocal gliosis, cavitation, central chromatolysis, neuronal degeneration and necrosis, perineuronal and perivascular edema in the all regions of the brain and acute neuronal necrosis in the gray matter of ventral horn of the spinal cord were also seen.Conclusion Our study suggested that the sheep fetuses are fully susceptible to viral infections and may even develop neurolopathological lesions upon natural infection with mentioned pathogens .Therefore ,according to ,specific lesions caused by viral infections, we believe that the histopathological pattern were detected in this study could be associated with either viral infection and or mainly by a Bunyavirus / or Flavivirus strains that extensively shares common lesions with Rift Valley fever ,Wesselsbron ,Cache valley virus / or and Akabaneviruses.Virtual SlidesThe virtual slide(s) for this article can be found here:
    Diagnostic Pathology 11/2014; 9(1):223. · 2.41 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To describe the seroprevalence rate of bluetongue virus (BTV) in goat flocks in southeast of Iran.
    Asian Pacific Journal of Tropical Biomedicine 05/2014; 4(Suppl 1):S275-8.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Aim: Bluetongue virus (BTV) is an economically important Orbivirus of the Reoviridae family, causes a haemorrhagic disease mainly in sheep and occasionally in cattle and some species of deer. The aim of this study was to describe the seroprevalence rate of bluetongue virus (BTV) in sheep in Kurdistan province, west of Iran. Also the history and epizootiology of bluetongue (BT) infection in Iran are reviewed. Study Design: method depends on Competitive Enzyme-Linked Immunosorbent Assay (c-ELISA). Place and Duration of Study: Departments of Veterinary, Agricultural and Natural Resources Research Center and Departments of Animal Virus Disease, Razi Vaccine and Serum Research Institute, in west of Iran during 2011-2012. Methodology: A total of 297 field sera collected from Healthy sheep with no symptoms in western Iran were screened for the present of group-specific BTV antibodies by competitive ELISA (c-ELISA). Results: The overall BTV antibodies prevalence was 42.42% in sheep (at 95% confidence level). Also a result was showed a significant increase in seroprevalence BT antibodies with classes of age. Conclusion: This investigation evaluates the present status of BT in western Iran. As well as the outbreak of BT in farm animals in the country was not recorded. A serological survey has indicated the presence of bluetongue virus (BTV) antibodies in sheep, goats, cattle and other farm animals in several states in Iran. However, clinical BT has not been observed in farm animals to date. BTV has not been isolated from Culicoides midges, although virus serotypes 3, 4, 9, 16, 20 and 22 were isolated in Iran.
    Journal of Scientific Research & Reports. 01/2014; 3(6):787-798.

Full-text (2 Sources)

Available from
Jul 3, 2014