Choleretic effect and intestinal propulsion of ‘mate’ (Ilexparaguariensis) and its substitutes or adulterants

Cátedra de Farmacologı́a, Facultad de Farmacia y Bioquı́mica, Junı́n 956 (1113) Buenos Aires, Argentina
Journal of Ethnopharmacology (Impact Factor: 2.94). 06/2001; 75(2-3):291-294. DOI: 10.1016/S0378-8741(01)00179-9

ABSTRACT ‘Mate’ or ‘Yerba mate’ (Ilexparaguariensis, Aquifoliaceae) is a tonic and stimulant beverage widely used in South America. It is also traditionally used in gastrointestinal disorders as eupeptic and choleretic agent. Accordingly, the effect of decoctions of the leaves of I.paraguariensis and three of its substitutes or adulterants (Ilexbrevicuspis, Ilexargentina and Ilextheezans) on bile flow (BF) and intestinal propulsion were investigated. I.paraguariensis and I.brevicuspis induced an increase in BF, while the latter also enhanced intestinal transit. In contrast, neither I.argentina nor I.theezans exerted any effect on BF or intestinal propulsion. These results suggest that the therapeutic properties of I. paraguariensis will be affected when at least an adulterant is present in the final commercial product of Yerba mate.

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