Article

Phytotoxic constituents from Nimbya alternantherae

Depto Fitopatologia, Universidade Federal de Viçosa, 36571-000 Viçosa, MG, Brazil
Biochemical Systematics and Ecology (Impact Factor: 1.17). 11/2006; 34(11):790-795. DOI: 10.1016/j.bse.2006.06.008

ABSTRACT A phytotoxic compound identified as 6-(3,3-dimethylallyloxy)-4-methoxy-5-methylphthalide (1), was isolated from the phytopathogenic fungus Nimbya alternantherae, cultivated on solid media. Catalytic hydrogenation of 1 resulted in the quantitative formation of second compound (2). Both compounds (1, 2) act by inhibiting the ATP synthesis in spinach thylakoids. A detailed investigation on the mechanism of action indicates that compound 1 acts as a Hill reaction inhibitor and uncoupler of photosynthesis.

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Aug 12, 2014