Determination of sialic acid and gangliosides in biological samples and dairy products: A review

Department of Nutrition and Food Chemistry, Faculty of Pharmacy, University of Valencia, Avda. Vicente Andrés Estellés s/n, 46100, Burjassot (Valencia), Spain; Hero Institute for Infant Nutrition, 30820, Alcantarilla, Spain
Journal of pharmaceutical and biomedical analysis (Impact Factor: 2.45). 01/2010; DOI: 10.1016/j.jpba.2009.04.023

ABSTRACT Gangliosides are sphingolipids containing one or more moieties of sialic acid in their structure. Both gangliosides and sialic acid are bioactive compounds related to animal physiology. Due to their biological relevance, analytical methods adapted to each type of matrix have been developed over time. The present study reviews the main methods applied to the analysis of sialic acid and gangliosides in biological samples and dairy products.

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