Effect of colchicine on transport of amine storage granules in sympathetic nerves of rat

Institute of Neurobiology, University of Göteborg, Göteborg, Sweden
European Journal of Pharmacology (Impact Factor: 2.68). 01/1969; DOI: 10.1016/0014-2999(68)90165-9

ABSTRACT Local application of colchicine to adrenergic ganglia and axons seems to interrupt the fast proximo-distal transport of amine storage granules. This effect may be due to destruction of neurotubules, which possibly take part in granular transport.

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