The colorectal malignant polyp: Scoping a dilemma

“Regina Elena” National Cancer Institute, Rome, Italy
Digestive and Liver Disease (Impact Factor: 2.89). 02/2007; DOI: 10.1016/j.dld.2006.06.039
Source: PubMed

ABSTRACT Colorectal adenomas containing invasive carcinoma represent the majority of early colorectal cancers. The malignant polyp carries a significant risk of lympho-haematic metastasis and mortality due to the penetration of cancerous cells into the submucosal layer. The therapeutic dilemma is whether to perform endoscopic or surgical resection. A thorough assessment of the endoscopic, histological and clinical variables is needed to unravel the best treatment for each patient. In particular, a unique staging of such lesions, based on certain histopathological features, has been deeply implicated in the therapeutic choice. Aim of this article is to review the main endoscopic, histological and clinical features of the malignant polyp in order to propose a systematic management of this lesion.

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