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    ABSTRACT: The authors report the prevalence of dementia in a community-dwelling Brazilian elderly population and correlate prevalence data with educational and socioeconomic levels. The study was conducted in Catanduva, Brazil. A total of 1,656 randomly selected subjects aged 65 years or more were submitted to a health questionnaire, the Mini-Mental State Examination (MMSE), and the Pfeffer Functional Activities Questionnaire (PFAQ). According to the PFAQ and MMSE scores, selected subjects were submitted to clinical, neurologic, and cognitive evaluations. The subjects diagnosed with dementia underwent laboratory tests and brain computed tomography (CT). Dementia was diagnosed in 118 subjects, corresponding to a prevalence of 7.1%. The main clinical diagnoses were Alzheimer disease (AD; 55.1%), vascular dementia (9.3%), and AD with cerebrovascular disease (14.4%). The prevalence increased with age and was higher in women. There was an inverse association with education (3.5% among persons with 8 or more years of schooling to 12.2% among those who were illiterate). Multivariate analysis disclosed significant association between these three variables and dementia. The prevalence of dementia in this Brazilian population was 7.1%, and AD was the most frequent diagnosis. Age, female gender, and low educational level were significantly associated with a higher prevalence of dementia.
    Alzheimer Disease and Associated Disorders 16(2):103-8. · 2.73 Impact Factor
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    ABSTRACT: Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence. To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment. A community sample of 1045 dementia-free individuals aged 75 years and over was examined by neuropsychological testing in a three-wave longitudinal study. Prevalence rates ranged from 3% to 20%, depending on the concept applied. The annual incidence rates applying different case definitions varied from 8 to 77 per 1000 person-years. Rates of conversion to dementia over 2.6 years ranged from 23% to 47%. Mild cognitive impairment is frequent in older people. Prevalence, incidence and predictive validities are highly dependent on the diagnostic criteria applied.
    The British Journal of Psychiatry 06/2003; 182:449-54. · 6.61 Impact Factor
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    ABSTRACT: Background: Awareness of disease is a concept related to the recognition of deficits, lack of knowledge of cognitive deficits or, also, to the awareness of deficits in activities of daily living in Alzheimer's disease. Objective: This review aimed at comparing definitions and etiological hypotheses for awareness of disease in Alzheimer's disease. Method: Search of prospective, retrospective, longitudinal, and cross-sectional articles at ISI, Medline, Lilacs and SciELO databases from 1984 to 2004 using the key-words awareness of deficit, awareness of disease, insight and Alzheimer's disease. Articles were examined to evaluate the definition of awareness of disease and divided by areas according to the objective. Results: The con- cepts of awareness of disease, awareness of deficit, awareness of cognitive deficit, insight,
    Revista De Psiquiatria Clinica - REV PSIQUIATR CLIN. 01/2006; 33(6).

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