Evaluation of Two Commonly Used Temporary Skin Dressings for the Treatment of Acute Partial-Thickness Wounds in Rats
ABSTRACT There is a broad range of expensive temporary wound dressings that promise better results in wound management. The aim of this study was to compare two commonly used temporary dressings for the treatment of partial-thickness wounds in a rat model.
Forty-two partial thickness wounds were created on the back of Lewis rats and treated with the dressings; control wounds remained without treatment. Wound size was determined daily by measuring the scabbed area. Three months after the wounds were created, skin elasticity was measured and a histologic evaluation was performed.
Wound appearance in the animals in the treated groups did not differ significantly. Wound closure was slower in the control group than in the dressing groups. There was no histologic evidence of inflammation and no suggestion of epidermal changes in any group.
Using both skin dressings, we observed satisfying results without any significant differences. Because of rising health care expenses, cost should play an essential role in the clinical application of these dressings.
Article: Skin substitutes in burns.Burns 04/1999; 25(2):97-103. DOI:10.1016/S0305-4179(98)00176-4 · 1.84 Impact Factor
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ABSTRACT: Sixteen patients with various degrees of postburn hypertrophic scars were evaluated by ultrasonography and elastometry. An Aloka Echo Camera (SSD-500) with a 7.5 MHz probe and a Cutometer SEM 575 skin elastometer were used. Serial monthly examinations were performed using both pieces of equipment. In some patients, more than one scar was assessed. The assessments were correlated with clinical grading of the progress of the scars. It was noted that ultrasonography was very sensitive in the localization of scar tissues, distinguishing them from normal skin, assessment of thickness and also delineation of the extent of scar tissues. The subcutaneous part of the scar could be assessed. Cutometer SEM 575 is a new machine that applies a gentle suction to the skin to measure its viscoelasticity. It is sensitive, the inter-observer variation is low, and it could be used for the grading of a scar. These two assessment techniques compliment other methods of scar assessment and will prove useful when assessment of response to treatment is required.Burns 04/1997; 23 Suppl 1:S12-8. DOI:10.1016/S0305-4179(97)90095-4 · 1.84 Impact Factor
Archives of Dermatology 03/2004; 140(2):160-2. DOI:10.1001/archderm.140.2.160 · 4.31 Impact Factor