Herbal remedies and their adverse effects in Tem tribe traditional medicine in Togo.

Centre de Formation et de Recherche sur les Plantes Médicinales (CERFOPLAM), Université de Lomé, Lomé, Togo.
African Journal of Traditional, Complementary and Alternative Medicines (Impact Factor: 0.56). 01/2011; 8(1):45-60. DOI: 10.4314/ajtcam.v8i1.60522
Source: PubMed


In Africa, up to 80% of the population relies on herbal concoctions for their primarily health care. In Togo, western Africa, Tem tribe is a population with old knowledge of medicinal plants, however, still very little is known about their medical practices. The present study was conducted to access for the apprehension of adverse effects of traditional remedies by Tem traditional healers (TH). Enquiry was performed by interviews with healers from August to October 2007 in Tchaoudjo prefecture (Togo). The study allowed us to interview 54 TH including 41(75.93%) males and 13(24.07%) females, who cited 102 recipes assumed to have adverse effects. The recipes were used alone to cure several diseases including haemorrhoids (22.55%), female sexual disorders and infertility (21.57%), gastrointestinal disorders (18.63%), and malaria (6.86%). A total of 34 plants belonging to 21 families were cited to be components of the recipes. Euphorbiaceae and Mimosaceae families were the most represented, however, Nauclea latifolia, Khaya senegalensis, Pseudocedrela kotschyi and Xeroderris stuhlmannii were the main components of recipes linked to adverse effects. A total of 20 adverse effects were linked to the administration of theses drugs, and among them; diarrhoea, abdominal pains, polyuria, general weakness and vomiting were the most frequently encountered. These findings were in accordance with several reports of the literature concerning medicinal plants, although they were based on empirical observations. Laboratory screenings are needed to access for the effectiveness as well as the possible toxic effects of the recipes.

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Available from: Simplice Damintoti Karou, May 13, 2015
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    • "The majority of the Togolese people living in the rural areas traditionally use plants for food and medicine. As in the other African countries, in recent years, the plants used traditionally for therapeutic purposes have attracted the attention of researchers (Karou et al., 2003, 2005, 2006; Koudouvo et al., 2011; Tchacondo et al., 2011). "
    Pan African Medical Journal 01/2015; 20. DOI:10.11604/pamj.2015.20.437.5660
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    • "Nauclea latifolia belongs to Rubiaceae family and is a small tree found in tropical areas in Africa. It is used in traditional medicine to treat malaria, epilepsy, anxiety, pain, fever [5,6]. Moreover, root stem of this plant is traditionally and empirically used by diabetic patients in Benin to manage their glycemia. "
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    ABSTRACT: Background Populations in Africa mostly rely on herbal concoctions for their primarily health care, but so far scientific studies supporting the use of plants in traditional medicine remain poor. The present study was undertaken to evaluate the anti-hyperglycemic effects of Picralima nitida (seeds), Nauclea latifolia (root and stem) and Oxytenanthera abyssinica (leaves) commonly used, in diabetic pregnancy. Methods Pregnant wistar rats, rendered diabetic by multiple low injections of streptozotocin, were treated with selected plant extracts based on their antioxidant activities. Vitamin C concentrations, fatty acid compositions and phytochemical analysis of plants extracts were determined. Effect of selected plant extracts on human T cell proliferation was also analysed. Results All analysed plant extracts exhibited substantial antioxidant activities probably related to their content in polyphenols. Picralima nitida exhibited the highest antioxidant capacity. Ethanolic and butanolic extracts of Picralima nitida, butanolic extract of Nauclea latifolia and ethanolic extract of Oxytenanthera abyssinica significantly decreased hyperglycemia in the diabetic pregnant rats. Butanolic extract of Picralima, also appeared to be the most potent immunosuppressor although all of the analysed extracts exerted an immunosuppressive effect on T cell proliferation probably due to their linolenic acid (C18:3n-3) and/or alkaloids content. Nevertheless, all analysed plants seemed to be good source of saturated and monounsaturated fatty acids. Conclusion By having antioxidant, anti-hyperglycemic and immunosuppressive activities, these plants could be good candidates in the treatment of diabetes and diabetic pregnancy.
    BMC Complementary and Alternative Medicine 04/2013; 13(1):77. DOI:10.1186/1472-6882-13-77 · 2.02 Impact Factor
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    • "There are also other original traditional medicines. In Africa, up to 80% of the population relies on herbal concoctions for their primary health care needs[5]. The Kagera region of northwestern Tanzania has a rich culture of original traditional medicine use and practice [6]. "
    01/2013; DOI:10.5772/56817
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