Nutrient-enriched formula versus standard term formula for preterm infants following hospital discharge (Review)

Hull York Medical School & Centre for Reviews and Dissemination, University of York, York, UK.
Cochrane database of systematic reviews (Online) (Impact Factor: 6.03). 03/2012; 3(3):CD004696. DOI: 10.1002/14651858.CD004696.pub4
Source: PubMed


Preterm infants are often much smaller than term infants by the time that they are discharged home from hospital. This review attempted to identify trial evidence about whether feeding these infants with formula enriched with nutrients rather than ordinary formula designed for term infants increased growth rates and improved development. We found 15 trials but these did not provide strong or consistent evidence that unrestricted feeding with nutrient-enriched formula affects growth and development up to about 18 months of age. Long-term growth and development has not yet been assessed.

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    • "Our findings are consistent with other studies [16-20] that investigated the effect of protein and energy supplementation after discharge on preterm infants’ neurodevelopment. However, it must be underlined that in all but one (ref. "
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