The Ethics of a Genetic Screening Study for Antisocial Personality Disorder With Mesoamericans Case Study in the Ethics of Mental Health Research

Hospital Nacional Rosales, San Salvador, El Salvador.
The Journal of nervous and mental disease (Impact Factor: 1.81). 03/2012; 200(3):260-4. DOI: 10.1097/NMD.0b013e318247d23e
Source: PubMed

ABSTRACT This article contains an analysis of a research ethics committee's (REC) concerns about a study protocol involving genetic screening for antisocial personality disorder. The study was proposed by US university researchers and to be conducted with Mesoamerican populations in the United States and in their countries of origin. The analysis explains why the study was not considered ethical by the REC, pointing to issues with the choice of study population, informed consent, confidentiality, and posttrial obligations. Some recommendations are provided for ways in which the study could have been redesigned.

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