Kikuchi-Fujimoto Disease: A 15-Year Analysis at a Children's Hospital in the United States

University of Texas Southwestern Medical Center, Dallas, TX, USA
Clinical Pediatrics (Impact Factor: 1.15). 02/2012; 52(1). DOI: 10.1177/0009922811436338
Source: PubMed
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    • "In addition, for our search, those articles that did not provide the ethnicity, age, and gender of the patients studied were not included in our review. We focused our review on the adult population although it is known that KFD may also occur in children.6 A total of 22 cases with KFD have been fully described in the literature.7–24 "
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    ABSTRACT: Kikuchi-Fujimoto Disease (KFD), also known as histiocytic lymphadenitis, is a benign, self-limiting disease that manifests primarily as cervical lymphadenopathy but may include low-grade fever, headache, and fatigue. There is a higher incidence of KFD in women aged 20-35 years and in Asian populations. A PubMed search revealed 590 articles that described KFD. Of these, 22 cases have been fully described in the United States. Ten of the 22 (45%) patients were male and 12 (55%) were female, with 20% Caucasian, 20% Asian American, and the remaining 60% of other ethnic backgrounds. In this study, we describe an additional 3 cases of KFD and discuss the diagnosis, pathology, and management of KFD.
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