Article

A Crossover Trial of Antimicrobial Scrubs to Reduce Methicillin-Resistant Staphylococcus aureus Burden on Healthcare Worker Apparel

Epidemiology and Infection Control, Virginia Commonwealth University, Richmond, Virginia WI 53705, USA.
Infection Control and Hospital Epidemiology (Impact Factor: 3.94). 03/2012; 33(3):268-75. DOI: 10.1086/664045
Source: PubMed

ABSTRACT The impact of antimicrobial scrubs on healthcare worker (HCW) bacterial burden is unknown. Objective. To determine the effectiveness of antimicrobial scrubs on hand and apparel bacterial burden.
Prospective, crossover trial.
Thirty HCWs randomized to study versus control scrubs in an intensive care unit.
Weekly microbiology samples were obtained from scrub abdominal area, cargo pocket, and hands. Mean log colony-forming unit (CFU) counts were calculated. Compliance with hand hygiene practices was measured. Apparel and hand mean log CFU counts were compared.
Adherence measures were 78% (910/1,173) for hand hygiene and 82% (223/273) for scrubs. Culture compliance was 67% (306/460). No differences were observed in bacterial hand burden or in HCWs with unique positive scrub cultures. No difference in vancomycin-resistant enterococci (VRE) and gram-negative rod (GNR) burden was observed. A difference in mean log methicillin-resistant Staphylococcus aureus (MRSA) CFU count was found between study and control scrubs for leg cargo pocket (mean log CFUs, 11.84 control scrub vs 6.71 study scrub; [Formula: see text]), abdominal area (mean log CFUs, 11.35 control scrub vs 7.54 study scrub; [Formula: see text]), leg cargo pocket at the beginning of shift (mean log CFUs, 11.96 control scrub vs 4.87 study scrub; [Formula: see text]), and abdominal area pocket at the end of shift (mean log CFUs, 12.14 control scrubs vs 8.22 study scrub; [Formula: see text]).
Study scrubs were associated with a 4-7 mean log reduction in MRSA burden but not VRE or GNRs. A prospective trial is needed to measure the impact of antimicrobial impregnated apparel on MRSA transmission rates.

Download full-text

Full-text

Available from: Kakotan Sanogo, Aug 15, 2014
2 Followers
 · 
263 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: Healthcare worker attire may become contaminated with pathogenic organisms during a normal shift. We performed a randomized crossover study to assess whether treatment with an antimicrobial coating would decrease bacterial contamination on scrubs. Thirty percent of all scrubs were contaminated; there was no difference in the rate of contamination between the intervention and control groups.
    Infection Control and Hospital Epidemiology 11/2014; 35(11):1411-3. DOI:10.1086/678426 · 3.94 Impact Factor
  • American Journal of Medical Quality 10/2014; 29(6). DOI:10.1177/1062860614550582 · 1.78 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: BACKGROUND: Healthcare workers' (HCWs) uniforms become contaminated with bacteria during normal use, and this may contribute to hospital-acquired infections. Antimicrobial uniforms are currently marketed as a means of reducing this contamination. OBJECTIVE: To compare the extent of bacterial contamination of uniforms and skin when HCWs wear 1 of 2 antimicrobial scrubs or standard scrubs. DESIGN: Prospective, randomized, controlled trial. SETTING: University-affiliated, public safety net hospital PARTICIPANTS: Hospitalist physicians, nurse practitioners, physician assistants, housestaff, and nurses (total N = 105) working on internal medicine units. INTERVENTION: Subjects were randomized to wear standard scrubs or 1 of 2 antimicrobial scrubs. MEASUREMENTS: Bacterial colony counts in cultures taken from the HCWs' scrubs and wrists after an 8-hour workday. RESULTS: The median (interquartile range) total colony counts was 99 (66-182) for standard scrubs, 137 (84-289) for antimicrobial scrub type A, and 138 (62-274) for antimicrobial scrub type B (P = 0.36). Colony counts from participants' wrists were 16 (5-40) when they wore standard scrubs and 23 (4-42) and 15 (6-54) when they wore antimicrobial scrubs A and B, respectively (P = 0.92). Resistant organisms were cultured from 3 HCWs (4.3%) randomized to antimicrobial scrubs and none randomized to standard scrubs (P = 0.55). Six participants (5.7%) reported side effects to wearing scrubs, all of whom wore antimicrobial scrubs (P = 0.18). CONCLUSIONS: We found no evidence that either antimicrobial scrub product decreased bacterial contamination of HCWs' uniforms or skin after an 8-hour workday. Journal of Hospital Medicine 2013;. © 2013 Society of Hospital Medicine.
    Journal of Hospital Medicine 07/2013; 8(7). DOI:10.1002/jhm.2051 · 2.08 Impact Factor