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Noninvasive in vitro measurement of pig-blood D-glucose by using a microwave cavity sensor

Department of Physics and Basic Science, Sogang University, Seoul, Republic of Korea.
Diabetes research and clinical practice (Impact Factor: 2.54). 02/2012; 96(3):379-84. DOI: 10.1016/j.diabres.2012.01.018
Source: PubMed

ABSTRACT We have developed an electromagnetic microwave cavity sensor based on the resonant frequency shift for real time measurement of the glycemia in pig blood. We could determine the concentration of d-glucose in pig blood in the range of 150-550mg/dl at the resonance frequency near 4.75GHz with a bandwidth of 300MHz. The change in the d-glucose concentration in blood brings microwave reflection coefficient S(11) changes of about 6.26dB and resonance frequency shifts of about 11.25MHz due to the electromagnetic interaction between the cavity resonator and the blood filled plastic tube inserted into the cavity. This proposed system provides a unique approach for real time noninvasive and contactless glucose monitoring.

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Available from: Arsen Babajanyan, Feb 02, 2015
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    • "A similar structure has been later used by the same authors as a biosensor for monitoring the glucose concentration in water [14]. A microwave biosensor based on a waveguide cavity resonator has been developed in [15] for non-invasive in-vitro measuring of pig blood D-glucose. A device based on an open-ended coaxial resonator embedded in a microfluidic chip has been recently proposed in [16] for compositional analysis of solvents at microwave frequencies. "
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