Bartonella vinsonii Endocarditis in an Adolescent With Congenital Heart Disease
ABSTRACT We report the second human case of Bartonella vinsonii subsp. berkhoffii endocarditis in a 19-year-old male with congenital heart disease. Diagnosis was established by Bartonella antibodies detected by immunofluorescence, and polymerase chain reaction amplification and sequencing from blood.
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- "vinsonii subsp. berkhoffii)   , Bartonella tamiae (B. tamiae)  , Bartonella rochalimae (B. "
ABSTRACT: In this article, authors review the current knowledge of Bartonella infection in small mammals including rodents, insectivores, bats and exotic small mammal pets and their vectors in Asia. Species of Bartonella are Gram-negative intracellular bacteria that infect erythrocytes of various mammalian and non-mammalian animals and mainly transmitted by blood sucking arthropod vectors. The genus Bartonella includes several species of important human diseases with severe clinical signs. Several new Bartonella species were isolated from rodents and other small mammals, and from human patients in Asia. Bartonella species are identified using standard polymerase chain reaction amplification and a sequencing targeting two housekeeping genes (gltA and rpoB) and the internal transcribed spacer fragment. Authors also discuss the implications in term of potential emerging zoonotic diseases.Asian Pacific Journal of Tropical Biomedicine 10/2014; 4(10):757-767. DOI:10.12980/APJTB.4.2014C742
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ABSTRACT: Bartonella spp. are fastidious bacteria that cause blood culture-negative endocarditis and which have been increasingly reported. We included all patients retrospectively and prospectively diagnosed with Bartonella endocarditis in our reference center between 2005 and 2013. Our diagnosis was based on the modified Duke criteria and on microbiological findings, including serological and PCR results. To review the published literature, we searched all human Bartonella endocarditis cases published between January 2005 and October 2013 in the PubMed database. We report a large series of 106 cases, which include 59 cases that have not previously been reported or mentioned. Indirect immunofluorescence assays, western blotting and RT-PCR from total blood, serum and valve tissue exhibited sensitivities of 58, 100, 33, 36 and 91%, respectively. The number of cases reported in the literature between 2005 and 2013 has increased to reach a cumulative number of 196 cases. The number of cases reported in the literature by other centers is increasing more rapidly than those diagnosed by our French reference center (p<10(-2)). Currently, there is a lack of criteria for the diagnosis of Bartonella endocarditis. We suggest that a positive PCR result from a cardiac valve or blood specimen, an IgG titer ≥800 using IFA or a positive western blot may be considered as major Duke criteria for Bartonella endocarditis. There is no real increase in the incidence of these infections but rather a better understanding and interest in the disease resulting from the improvement of diagnostic tools. Copyright © 2014, American Society for Microbiology. All Rights Reserved.Journal of Clinical Microbiology 12/2014; 53(3). DOI:10.1128/JCM.02827-14 · 3.99 Impact Factor
Chapter: Chapter 105. BartonellaMolecular Medical Microbiology, second edited by tang, 12/2015: chapter 105; Academic Press.