Regulation of DNA glycosylases and their role in limiting disease.

Center for Research on Occupational and Environmental Toxicology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239 - 3098, USA.
Free Radical Research (Impact Factor: 3.28). 02/2012; 46(4):460-78. DOI: 10.3109/10715762.2012.655730
Source: PubMed

ABSTRACT This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.

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