Article

Cinical research Reliability and validity of the Repeatable Battery for the Assessment of Neuropsychological Status in community-dwelling elderly

Department of Psychiatry, Tongji Hospital, Shanghai, China.
Archives of medical science : AMS 10/2011; 7(5):850-7. DOI: 10.5114/aoms.2011.25561
Source: PubMed

ABSTRACT The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a widely used screening instrument in neuropsychological assessment and is a brief, individually administered measure. The present study aims to assess the reliability and validity of the Chinese version of the RBANS in community-dwelling elderly.
All subjects come from the community-dwelling elderly in Shanghai, China. They completed a questionnaire concerning demographic information, the mini-mental state examination (MMSE) and the Chinese version of the RBANS. To test for internal consistency, Cronbach's α was calculated for all six RBANS indices. Correlations between each of the RBANS and MMSE subtests were conducted to measure the concurrent validity. A confirmatory factor analysis (CFA) was conducted to test the construct validity.
The final sample of participants included 236 community-dwelling elderly. The mean total score on the RBANS was 86.02 (±14.19). The RBANS total score showed strong internal consistency (r = 0.806), and the coefficient α value for each of the RBANS scales ranged from 0.142 to 0.727. The total RBANS score was highly correlated with that of the MMSE (r = 0.594, p<0.001), and the RBANS subtests also demonstrated strong correlations with most of the MMSE subtests. The results of the CFA indicated an acceptable fit between the Chinese version of the RBANS and the original.
The Chinese version of the RBANS had relatively good reliability and validity in a community-dwelling elderly sample. It may be a useful screening instrument for conducting cognitive assessments in community-dwelling elderly.

0 Followers
 · 
170 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Whether healthy older people can benefit from cognitive training (CogTr) remains controversial. This study explored the benefits of CogTr in community dwelling, healthy, older adults and compared the effects of single-domain with multi-domain CogTr interventions. A randomized, controlled, 3-month trial of CogTr with double-blind assessments at baseline and immediate, 6-month and 12-month follow-up after training completion was conducted. A total of 270 healthy Chinese older people, 65 to 75 years old, were recruited from the Ganquan-area community in Shanghai. Participants were randomly assigned to three groups: multi-domain CogTr, single-domain CogTr, and a wait-list control group. Twenty-four sessions of CogTr were administrated to the intervention groups over a three-month period. Six months later, three booster training sessions were offered to 60% of the initial training participants. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS, Form A), the Color Word Stroop test (CWST), the Visual Reasoning test and the Trail Making test (TMT) were used to assess cognitive function. Multi-domain CogTr produced statistically significant training effects on RBANS, visual reasoning, and immediate and delayed memory, while single-domain CogTr showed training effects on RBANS, visual reasoning, word interference, and visuospatial/constructional score (all P < 0.05). At the 12-month posttest, the multi-domain CogTr showed training effects on RBANS, delayed memory and visual reasoning, while single-domain CogTr only showed effects on word interference. Booster training resulted in effects on RBANS, visual reasoning, time of trail making test, and visuospatial/constructional index score. Cognitive training can improve memory, visual reasoning, visuospatial construction, attention and neuropsychological status in community-living older people and can help maintain their functioning over time. Multi-domain CogTr enhanced memory proficiency, while single-domain CogTr augmented visuospatial/constructional and attention abilities. Multi-domain CogTr had more advantages in training effect maintenance. Chinese Clinical Trial Registry. Registration number: ChiCTR-TRC-09000732.
    BMC Medicine 03/2012; 10:30. DOI:10.1186/1741-7015-10-30 · 7.28 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The Saint Louis University Mental Status (SLUMS) examination is a popular screening scale for cognitive impairment in North America but has not been studied in Chinese populations. The aim of this study is to compare consistency of the SLUMS with the Chinese version of Mini-Mental Status Examination (CMMSE) and the Beijing version of Montreal Cognitive Assessment (MoCA-B) in Chinese elderly. Two hundred seventy-eight Chinese elderly with chronic diseases and geriatric syndromes from the geriatrics department were screened for cognitive impairment, including dementia and mild cognitive impairment, using SLUMS, CMMSE, and MoCA-B. The modified education level cutoff in the diagnostic criteria of SLUMS (mSLUMS) was explored. Scores of the scales and classifications for cognitive status by them were compared using Spearman and κ statistics, respectively. Spearman correlation coefficient between scores of the scales were 0.747 (SLUMS vs CMMSE, P < .001), 0.839 (SLUMS vs MoCA-B, P < .001), and 0.773 (CMMSE vs MoCA-B, P < .001). For detection of dementia, κ values were 0.462 (SLUMS vs CMMSE, P < .000) and 0.484 (mSLUMS vs CMMSE, P < .000). For mild cognitive impairment, κ values were 0.123 (SLUMS vs CMMSE plus MoCA-B in parallel, P = .089) and 0.148 (mSLUMS vs CMMSE plus MoCA-B in parallel, P = .031). For all cognitive impairment, κ values were 0.562 (SLUMS vs MoCA-B, P < .000) and 0.650 (SLUMS vs MoCA-B, P < .000). Findings from our study indicate that the scores of SLUMS are fairly consistent with MoCA-B and CMMSE in Chinese elderly. Discrepancies of classifications for cognitive status by SLUMS and the other 2 scales implies that further work is needed to explore optimal cutoffs of SLUMS for screening mild cognitive impairment and dementia in elderly Chinese.
    Journal of the American Medical Directors Association 06/2012; 13(7):626-9. DOI:10.1016/j.jamda.2012.05.003 · 4.78 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: OBJECTIVE The α7 nicotinic acetylcholine receptor (nAChR) is associated with cognitive and P50 auditory gating deficits in schizophrenia, and α7 nAChR agonists can potentially reverse these deficits. The authors examined multiple dosages of tropisetron, a partial agonist at the nAChR, for short-term effects on cognition and P50 deficits in schizophrenia. METHOD In a randomized double-blind design, 40 nonsmoking patients with schizophrenia who had P50 ratios greater than 0.5 and were stabilized on 3-6 mg/day of risperidone were randomly assigned to receive placebo (N=10) or oral tropisetron at 5 mg/day (N=10), 10 mg/day (N=10), or 20 mg/day (N=10). The authors measured P50 inhibitory gating and administered the Chinese-language version of the Repeatable Battery for the Assessment of Neuropsychological Status at baseline and after 10 days of treatment. RESULTS After 10 days of treatment, all three daily doses of tropisetron significantly improved overall cognitive deficits, with 10 mg showing the greatest improvement for the immediate memory index score and 20 mg for the delayed memory index score on the cognitive battery. The P50 deficits were also improved, and that improvement was significantly correlated with cognitive improvement. Two patients in the 20 mg/day group dropped out because of adverse effects, but the other dosages were well tolerated. CONCLUSIONS The improvement of cognition with tropisetron appeared to be associated with normalization in P50 deficits. Thus, α7 nAChR agonists appear to be a promising therapeutic approach for the treatment of cognitive deficits that are related to abnormal P50 suppression in schizophrenia.
    American Journal of Psychiatry 09/2012; 169(9):974-81. DOI:10.1176/appi.ajp.2012.11081289 · 13.56 Impact Factor
Show more

Preview (2 Sources)

Download
2 Downloads
Available from