Article

Time to reflect on surgery and neuro-intervention for intracranial atherosclerotic diseases.

Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, 4/F, Clinical Science Building, The Chinese University of Hong Kong, 1 Ngan Shing Street, Shatin, New Territories, Hong Kong, China.
Journal of Clinical Neuroscience (impact factor: 1.25). 02/2012; 19(2):222-3. DOI:10.1016/j.jocn.2011.07.019 pp.222-3
Source: PubMed

ABSTRACT In view of the early results and halt of recruitment from both the Carotid Occlusion Surgery Study (COSS) and Stenting and the Aggressive Medical Therapy for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) study we should seize this opportunity to reflect on future directions, rather than abandoning these procedures, during this period of disillusionment. We here suggest the reasons for the failure of these two clinical trials and review future directions for researche in cerebral revascularization.

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Keywords

Aggressive Medical Therapy
 
Carotid Occlusion Surgery Study
 
cerebral revascularization
 
COSS
 
future directions
 
Intracranial Stenosis
 
Preventing Recurrent Stroke
 
review future directions
 
two clinical trials