Article

Resolution of isomeric multi-ruthenated porphyrins by travelling wave ion mobility mass spectrometry.

ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas, UNICAMP 13083-970, Campinas, SP, Brazil.
Rapid Communications in Mass Spectrometry (impact factor: 2.79). 02/2012; 26(3):263-8. DOI:10.1002/rcm.5314 pp.263-8
Source: PubMed

ABSTRACT The ability of travelling wave ion mobility mass spectrometry (TWIM-MS) to resolve cationic meta/para and cis/trans isomers of mono-, di-, tri- and tetra-ruthenated supramolecular porphyrins was investigated. All meta isomers were found to be more compact than the para isomers and therefore mixtures of all isomeric pairs could be properly resolved with baseline or close to baseline peak-to-peak resolution (R(p-p)). Di-substituted cis/trans isomers were found, however, to present very similar drift times and could not be resolved. N(2) and CO(2) were tested as the drift gas, and similar α but considerably better values of R(p) and R(p-p) were always observed for CO(2).

0 0
 · 
0 Bookmarks
 · 
49 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

baseline peak-to-peak resolution
 
cis/trans isomers
 
Di-substituted cis/trans isomers
 
drift gas
 
mixtures
 
tetra-ruthenated supramolecular porphyrins
 
TWIM-MS
 
wave ion mobility mass spectrometry