Article

Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation

Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA 22908, USA.
Skeletal Radiology (Impact Factor: 1.74). 03/2012; 41(3):357-60. DOI: 10.1007/s00256-011-1350-9
Source: PubMed

ABSTRACT Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.

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