Article

Metabolomics in cancer: A bench-to-bedside intersection.

Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Critical reviews in oncology/hematology (impact factor: 5.27). 03/2012; 84(1):1-7. DOI:10.1016/j.critrevonc.2012.02.009 pp.1-7
Source: PubMed

ABSTRACT The field of oncology is a rapidly evolving science mostly due to extensive basic, translational and clinical research which have provided more insights into the tumor biology and set grounds for the development of new therapies. Metabolomics is the upcoming new science in the omics field with the potential to further increment our knowledge of cancer biology. In this review we intend to explore the potential role of metabolomics in understanding cancer process, improving cancer staging, refining tumor characterization and in the search for predictive biomarkers of response and toxicity.

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Keywords

cancer biology
 
clinical research
 
evolving science
 
extensive basic
 
grounds
 
increment
 
Metabolomics
 
omics field
 
potential role
 
predictive biomarkers
 
refining tumor characterization
 
toxicity
 
tumor biology
 
upcoming new science