Silver-Mediated Oxidative C-H/C-H Functionalization: A Strategy To Construct Polysubstituted Furans
ABSTRACT A novel silver-mediated highly selective oxidative C-H/C-H functionalization of 1,3-dicarbonyl compounds with terminal alkynes for the creation of polysubstituted furans and pyrroles in one step has been demonstrated. Promoted by the crucial silver species, perfect selectivity and good to excellent yields could be achieved. This protocol represents an extremely simple and atom-economic way to construct polysubstituted furans and pyrroles from basic starting materials under mild conditions.
Advanced Synthesis & Catalysis 03/2015; DOI:10.1002/adsc.201400857 · 5.54 Impact Factor
Advanced Synthesis & Catalysis 02/2015; 357(2‐3):n/a-n/a. DOI:10.1002/adsc.201500006 · 5.54 Impact Factor
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ABSTRACT: A metal-free radical oxidative decarboxylation/cyclization of acyl peroxides and 2-isocyanobiphenyls was achieved, leading to 6-aryl phenanthridines as well as 6-alkyl phenanthridines in moderate to good yields. The procedure featured simple conditions and was metal-free and base free. It represents a practical approach to access 6-aryl/alkyl phenanthridines.Chemical Communications 02/2015; 51(18). DOI:10.1039/c4cc10015h · 6.72 Impact Factor