Parent psychopathology and offspring mental disorders: Results from the WHO World Mental Health Surveys
ABSTRACT Associations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity.
To examine the associations of parent with respondent disorders.
Data come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews.
Although virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle- than low-/lower-middle-income countries, and consistently higher for behaviour (11.0-19.9%) than other (7.1-14.0%) disorders.
Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.
- SourceAvailable from: Christopher P Salas-Wright
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- "Although there is empirical support for the relationship between childhood exposure to parental suicidal behavior and the development of suicidal behavior (Brent & Melhem, 2008; Bronisch & Lieb, 2008; Kuramoto et al., 2009; Wilcox et al., 2010), studies on the relationship between parental suicidal behavior and the development of SUDs are limited. The most recent WHO World Mental Health Survey study found that parental suicide attempt and/or death only significantly predicted substance abuse in offspring when both parents died of suicide (McLaughlin et al., 2012). Another study of young adults in Sweden found that those who had lost a parent to suicide during childhood were at higher risk for later hospitalization for drug use than those who had not (Wilcox et al, 2010). "
ABSTRACT: Childhood exposure to parental suicidal behavior has been linked to a variety of adverse behavioral and health outcomes. However, relatively little is known about the degree to which such exposure may place individuals at risk for a substance use disorder (SUD). Employing data from the National Epidemiologic Survey on Alcohol and Related Conditions, we compared the prevalence of SUDs among those who experienced childhood exposure to parental suicide attempts. Childhood exposure to parental suicide attempts was not associated with increased risk for the development of alcohol, cannabis, or cocaine use disorders. However, individuals who were exposed to aparental suicide attempt as children were significantly more likely to have met criteria for stimulant (AOR=1.40, 95% CI=1.18-1.67), sedative (AOR=1.24, 95% CI=1.04-1.47), tranquilizer (AOR=1.78, 95% CI=1.45-2.20), and opioid (AOR=1.41, 95% CI=1.19-1.67) use disorders in their lifetime. No significant gender differences were identified with respect to the magnitude of the relationship between exposure to parental suicide attempts and SUD risk among men and women. Findings suggest that, controlling for an array of sociodemographic, parental, mental health, and childhood adversity confounds, childhood exposure to parental suicide attempts is a vulnerability factor for low prevalence illicit drugs (i.e. stimulants, sedatives, tranquilizers, opioids), but not for more commonly used substances. Copyright © 2015 Elsevier Ltd. All rights reserved.Addictive Behaviors 03/2015; 46. DOI:10.1016/j.addbeh.2015.03.008 · 2.44 Impact Factor
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- "The CIDI-Auto is a structured diagnostic interview that can produce DSM-IV and ICD-10 diagnosis for mental health problems and substance abuse and dependence. The CIDI has high concurrent validity (McLaughlin et al., 2012). "
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