The virtual physiological human: challenges and opportunities.
ABSTRACT This paper summarises the current achievements and future developments of the virtual physiological human (VPH) technology. The VPH is an organised collection of computational frameworks and ICT-based tools for the multilevel modelling and simulation of the human anatomy and physiology. Once sufficiently developed, the VPH will provide an essential technological infrastructure to the Physiome Project, to pathology-specific initiatives in translational research, and to vertical solutions for the biomedical industry
- Isis 01/2003; 94(1):30-56. · 0.92 Impact Factor
Conference Proceeding: The Multimod Application Framework[show abstract] [hide abstract]
ABSTRACT: This paper presents the Multimod Application Framework, a software framework for the rapid development of computer-aided medicine applications. This framework, distributed under an open source licence, is being developed as part of the Multimod Project, a multi-national research endeavour partially supported by the European Commission through the Fifth Framework Programme. This application framework provides an effective re-use model for visualisation and data-processing algorithms that may be incorporated into the framework with moderate overhead and then made available to the biomedical research community as part of a complete set of applications.Information Visualisation, 2004. IV 2004. Proceedings. Eighth International Conference on; 08/2004
Conference Proceeding: Bridge ontology and its role in semantic annotation[show abstract] [hide abstract]
ABSTRACT: Multiontologies environment is common such as the semantic annotation applications based on multiontologies. Based on analyzing and classifying the relationships between multiontologies, we propose the idea of bridge ontology, and present its detailed structure too. To deal with the semantic annotation problem based on multiontologies, a new approach is proposed which employing bridge ontology to express the complex relationships between multiontologies. The bridge ontology is a peculiar ontology, which can be created and maintained conveniently, and is effective in the applications based on multiontologies. The approach using bridge ontology has the advantages of low-cost, scalable, robust in the Web circumstance, avoiding the unnecessary ontology extending and integration, and promoting ontology reuse.Cyberworlds, 2004 International Conference on; 12/2004