ReLiBase - An Object-Oriented Comprehensive Receptor/Ligand Database.
Article: [Protein structure and function].Nordisk medicin 11/1970; 84(47):1481-7.
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ABSTRACT: The design of an unprecedented multicomponent reaction to and synthesis of 2-amino-5-ketoaryl pyrroles are described. The compounds (14 examples) can be synthesized by reacting aminoacetophenone sulfonamides, (hetero)aromatic aldehydes, and malonodinitrile or cyanoacetic acid derivatives in one-pot manner. Pharmacophore features and potential applications of this new scaffold are discussed.Chemical Biology & Drug Design 03/2010; 75(3):277-83. · 2.47 Impact Factor
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