Portable Instrumentation Platform for Ecl-based Sensors and Biosensors.
Conference: BIODEVICES 2011 - Proceedings of the International Conference on Biomedical Electronics and Devices, Rome, Italy, 26-29 January, 2011
A new portable instrumentation platform for electrochemiluminescence (ECL)-based disposable sensors and biosensors is described. The reader unit consists of a potentiostat and a photodiode as light-to-current converter integrated in the same instrument. To check the performance of the instrument as sensors platform, two transduction chemistries (luminol and tris(2,2′bipyridyl)ruthenium(II)) and two widely used analytes (hydrogen peroxide and triethylamine) were selected. Additionally, different working modes have been implemented in the instrument: chronoamperometry and cyclic voltammetry. The calibration functions obtained show linear dependences with dynamic ranges from 0.01 to 0.07 mg·1-1 for H 2O2, 0.05-10.0 mg·1-1 for triethylamine with detection limits of 0.01 mg·1-1 for H2O 2 and 0.03 mg·1-1 for triethylamine and a sensor-to-sensor reproducibility (relative standard deviation RSD) around 8.2 % and 3.1 %, respectively at the medium level of the range.
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