Conference: Foundations on Natural and Artificial Computation - 4th International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2011, La Palma, Canary Islands, Spain, May 30 - June 3, 2011. Proceedings, Part I
[Show abstract][Hide abstract] ABSTRACT: Body temperature is a classical diagnostic tool for a number of diseases. However, it is usually employed as a plain binary classification function (febrile or not febrile), and therefore its diagnostic power has not been fully developed. In this paper, we describe how body temperature regularity can be used for diagnosis. Our proposed methodology is based on obtaining accurate long-term temperature recordings at high sampling frequencies and analyzing the temperature signal using a regularity metric (approximate entropy). In this study, we assessed our methodology using temperature registers acquired from patients with multiple organ failure admitted to an intensive care unit. Our results indicate there is a correlation between the patient's condition and the regularity of the body temperature. This finding enabled us to design a classifier for two outcomes (survival or death) and test it on a dataset including 36 subjects. The classifier achieved an accuracy of 72%.
[Show abstract][Hide abstract] ABSTRACT: Lempel–Ziv complexity (LZ) [J. Ziv, A. Lempel, On the complexity of finite sequences, IEEE Trans. Inform. Theory 22 (1976) 75–81] and its variants have been used widely to identify non-random patterns in biomedical signals obtained across distinct physiological states. Non-random signatures of the complexity measure can occur under nonlinear deterministic as well as non-deterministic settings. Surrogate data testing have also been encouraged in the past in conjunction with complexity estimates to make a finer distinction between various classes of processes. In this brief letter, we make two important observations (1) Non-Gaussian noise at the dynamical level can elude existing surrogate algorithms namely: Phase-randomized surrogates (FT) amplitude-adjusted Fourier transform (AAFT) and iterated amplitude-adjusted Fourier transform (IAAFT). Thus any inference nonlinear determinism as an explanation for the non-randomness is incomplete (2) Decrease in complexity can be observed even across two linear processes with identical auto-correlation functions. The results are illustrated with a second-order auto-regressive process with Gaussian and non-Gaussian innovations. AR(2) processes have been used widely to model several physiological phenomena, hence their choice. The results presented encourage cautious interpretation of non-random signatures in experimental signals using complexity measures.
[Show abstract][Hide abstract] ABSTRACT: A different method is proposed to detect deterministic structure from a pseudoperiodic time series. By using the correlation coefficient as a measure of the distance between cycles, we are exempt from phase-space reconstruction and further construct a hierarchy of pseudocycle series that, in turn, preserve less determinism than the original time series. Appropriate statistics are then devised to reveal the temporal and spatial correlation encoded in this hierarchy of the pseudocycle series, which allows for a reliable detection of determinism and chaos in the original time series. We demonstrate that this method can reliably identify chaos in the presence of noise of different sources for both artificial data and experimental time series.
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