Conference Paper

Translational Bioinformatics: Challenges and Opportunities for Case-Based Reasoning and Decision Support.

DOI: 10.1007/978-3-642-14274-1_1 Conference: Case-Based Reasoning. Research and Development, 18th International Conference on Case-Based Reasoning, ICCBR 2010, Alessandria, Italy, July 19-22, 2010. Proceedings
Source: DBLP


Translational bioinformatics is bioinformatics applied to human health. Although, up to now, its main focus has been to support
molecular medicine research, translational bioinformatics has now the opportunity to design clinical decision support systems
based on the combination of -omics data and internet-based knowledge resources. The paper describes the state-of-art of translational
bioinformatics highlighting challenges and opportunities for decision support tools and case-based reasoning. It finally reports
the design of a new system for supporting diagnosis in dilated cardiomyopathy. The system is able to combine text mining,
literature search and case-based retrieval.

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