Article

Pipecuronium versus high dose vecuronium. II. A comparison of speed of onset and cumulation during propofol anaesthesia.

Department of Anaesthesia, St Mary's Hospital, London.
Anaesthesia (Impact Factor: 3.49). 03/1992; 47(2):107-9. DOI: 10.1111/j.1365-2044.1992.tb02004.x
Source: PubMed

ABSTRACT The onset time and tendency to cumulation of pipecuronium and high-dose vecuronium were compared during nitrous oxide anaesthesia supplemented with a propofol infusion. Pipecuronium 0.06 mg.kg-1 had a similar duration of action to vecuronium 0.2 mg.kg-1 (49 vs 43). Patients who received vecuronium had a shorter onset time of neuromuscular blockade (p less than 0.01). Neither pipecuronium nor vecuronium showed marked cumulation.

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