Fuzzy logic analysis and reconstruction of bone structure from high-resolution MRI
ABSTRACT Bone fractures as a consequence of osteoporosis are becoming a major concern for the aging population. Quality of life may be dramatically affected by the disease and its consequences. Vertebroplasty is a nonsurgical therapy to strengthen an
osteoporotic bone. This is accomplished by injecting a medical cement mixture through a needle into the fractured bone. Understanding the rheology of the cement in the bone pore structure would improve the effectiveness of the treatment. Significant
progress has been made in the extraction of geometrical parameters describing the complicated morphological structure of trabecular bone from MR images. For example, the distance transform (DT) and more recently the fuzzy distance transform (FDT) methods were applied to the assessment of trabecular bone thickness. This methodological study focuses on combining high-resolution MRI together with advanced methods of image analysis, which is a 3D FDT, for the assessment of the key geometrical features of bone. The analysis is done at the pore, meso- and vertebral scale. The broader objective of this work is to have a better understanding of
geometrical changes associated with osteoporotic bones and emerging techniques to repair the fractured bone by the use of medical cements.