Article

Interactions of HTF4 with E-box motifs in the long terminal repeat of human immunodeficiency virus type 1

Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-1393.
Journal of Virology (Impact Factor: 4.65). 10/1992; 66(9):5631-4.
Source: PubMed

ABSTRACT We have identified three consensus E-box motifs in the long terminal repeat of human immunodeficiency virus type 1. One of these E boxes interacts selectively with representative members of the class A group of basic helix-loop-helix proteins, including HTF4, E47, and their heterodimers. Our analyses implicate the helix-loop-helix proteins in regulation of human immunodeficiency virus type 1 gene expression.

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