Electroanalytical properties of haemoglobin in silica-nanocomposite films electrogenerated on pyrolitic graphite electrode
ABSTRACT Haemoglobin (Hb) modified electrochemical devices have been prepared by Hb encapsulation in silica sol-gel films (SiO2), which were generated by electro-assisted deposition onto pyrolitic graphite electrodes (PGEs). The stability and electrocatalytic activity of Hb entrapped into SiO2 network was substantially enhanced in the presence of cationic surfactant (CTAB) and Au nanoparticles (Au-NPs). The composition of sol-gel synthesis medium, i.e., molar ratio of silica precursor to water, contents of Hb, CTAB and Au-NPs, as well as the conditions of electrogeneration had a great influence on the electrocatalytic activity of Hb on PGE surface. The electrochemical response of the PGE modified with the composite SiO2-Hb-CTAB-Au-NPs film was found to vary linearly with the concentration of dissolved oxygen in solution and this was exploited to determine this analyte in the tap water with detection limit 0.12 mg L-1. The electrocatalytic current of dissolved oxygen was also found to decrease in the presence of the antivirus drug--amino derivative of adamantane (rimantadine)--which opens the way to the determination of this drug with detection limit 0.3 mg L-1 using PGE modified with SiO2-Hb-CTAB-Au-NPs nanocomposite film.
Conference Paper: Parallel genetic algorithm for multiknapsack problem[Show abstract] [Hide abstract]
ABSTRACT: This paper begins by introducing the basic mechanics of genetic algorithm and discussing different ways to parallelize algorithm. A parallel genetic algorithm (PGA) is presented over a cluster of workstations by using the PVM library, which is used to handle communications among processors. Using the presented algorithm, the well-known 0-1 multiknapsack-problem is computed. Simulation results are presented to show how the performance of the PGA is affected by variations on the number of nodes, population size and migration interval. Results indicate that the performance of PGA on multiknapsack problem is sound and robust.Electrical and Computer Engineering, 2003. IEEE CCECE 2003. Canadian Conference on; 06/2003