International Journal of Pharmaceutical Sciences and Research 01/2011; 2:2031-2036.


Aegle marmelos Corr. (Rutaceae), commonly known as Bael, Bengal Quince
is a tree of Indian origin, well known from pre- historic time. Utilization of
bael fruit in day-to-day life has a great nutritional, environmental as well as
commercial importance. All the parts of this tree including stem, bark, root,
leaves, fruit and seeds at all stages of maturity has medicinal virtues and
has been used in Ethno-medicine to exploits its medicinal properties
including antidiarroheal, antidysentric, antipyretic and anti inflammatory
activities. Compounds purified from bael fruit have been proven to have
biological potential against several diseases like diabetes, gastric ulcer and
hyperlipidaemia. It should also be indicated that the therapeutic activities
of few isolated constituents have also proven to possess antibacterial,
antiviral, antioxidant and radioprotective activities. Thus the purpose of this
abstract is to explore the pharmacological potential of some crude extracts
of bael fruit.

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Available from: Rahul Kaushik, Oct 09, 2015
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    ABSTRACT: A total of 34 plant species belonging to 18 different families, selected on the basis of folklore medicinal reports practised by the tribal people of Western Ghats, India, were assayed for antibacterial activity against Escherichia coli, Klebsiella aerogenes, Proteus vulgaris, and Pseudomonas aerogenes (gram-negative bacteria) at 1000-5000 ppm using the disc diffusion method. Of these 16 plants showed activity; among them Cassia fistula, Terminalia arjuna and Vitex negundo showed significant antibacterial activity against the tested bacteria. Our findings confirm the traditional therapeutic claims for these herbs.
    Journal of Ethnopharmacology 10/1998; 62(2):173-82. DOI:10.1016/S0378-8741(98)00057-9 · 3.00 Impact Factor
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    ABSTRACT: Aegle marmelos (L.) Correa has been widely used in indigenous systems of Indian medicine due to its various medicinal properties. However, despite its traditional usage as an anti-diarrhoeal there is limited information regarding its mode of action in infectious forms of diarrhoea. Hence, we evaluated the hot aqueous extract (decoction) of dried unripe fruit pulp of A. marmelos for its antimicrobial activity and effect on various aspects of pathogenicity of infectious diarrhoea. The decoction was assessed for its antibacterial, antigiardial and antirotaviral activities. The effect of the decoction on adherence of enteropathogenic Escherichia coli and invasion of enteroinvasive E. coli and Shigella flexneri to HEp-2 cells were assessed as a measure of its effect on colonization. The effect of the decoction on production of E. coli heat labile toxin (LT) and cholera toxin (CT) and their binding to ganglioside monosialic acid receptor (GM1) were assessed by GM1-enzyme linked immuno sorbent assay whereas its effect on production and action of E. coli heat stable toxin (ST) was assessed by suckling mouse assay. The decoction showed cidal activity against Giardia and rotavirus whereas viability of none of the six bacterial strains tested was affected. It significantly reduced bacterial adherence to and invasion of HEp-2 cells. The extract also affected production of CT and binding of both LT and CT to GM1. However, it had no effect on ST. The decoction of the unripe fruit pulp of A. marmelos, despite having limited antimicrobial activity, affected the bacterial colonization to gut epithelium and production and action of certain enterotoxins. These observations suggest the varied possible modes of action of A. marmelos in infectious forms of diarrhoea thereby validating its mention in the ancient Indian texts and continued use by local communities for the treatment of diarrhoeal diseases.
    BMC Complementary and Alternative Medicine 11/2009; 9(Suppl 47):47. DOI:10.1186/1472-6882-9-47 · 2.02 Impact Factor
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    ABSTRACT: A new natural product oxazoline derivative named aeglemarmelosine (1) along with eight known compounds (2-9) were isolated from roots and twigs of Aegle marmelos. Compounds 1-6 were isolated from the roots whereas compounds 7-9 were obtained from twigs. Compounds 5 and 6 were also detected from the twigs. All structures were characterized by extensive 1D and 2D NMR spectroscopic methods.
    Journal of the Brazilian Chemical Society 01/2011; 22(1):176-178. DOI:10.1590/S0103-50532011000100024 · 1.13 Impact Factor
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