Jasminum grandiflorum Linn (Chameli): Ethnobotany, Phytochemistry and Pharmacology – A review

Pharmacologyonline 2 newsletter 2009; 586-595. Volume 2, (May- August 2009) (057). ISSN No. 1827-8620 01/2009; 2:586-595.


Jasminum grandiflorum Linn (Chameli / Yasmin; Oleaceae) is native to Tropical and warm Temperate regions and cultivated in France, Italy, China, Japan, India, Morocco and Egypt. The plant is documented to possess beneficial effects as odontalgic, thermogenic, aphrodisiac, antiseptic, emollient, anthelmintic, deobstruant, suppurative, tonic, in fixing loose teeth, ulcerative stomatitis, leprosy, skin diseases, ottorrhoea, otalgia, wounds, corns and aromatherapy. Pharmacological activities of the plant reported so far are spasmolytic, antiinflammatory, anti-microbial, antioxidant, antiulcer, cytoprotective, chemoprotective, wound healing and anti-acne activity. The present review is an attempt to highlight the various ethnobotanical and traditional uses as well as phytochemical and pharmacological activities reported so far from J. grandiflorum.

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    ABSTRACT: Jasminum grandiflorum belongs to the family Oleaceae and is known to have anti-inflammatory, antimicrobial, antioxidant, and antiulcer activities. The present study was undertaken to study its analgesic and anticonvulsant effects in rats and mice. The antinociceptive activity of the hydroalcoholic extract of J. grandiflorum leaves (HEJGL) was studied using tail flick and acetic acid - induced writhing method. Similarly, its anticonvulsant activity was observed by maximal electroshock (MES) method and pentylenetetrazol (PTZ) method. Statistical analysis was performed using one-way analysis of variance (ANOVA) followed by Dunnett's test. At doses of 50, 100, and 200 mg/kg, HEJGL showed significant analgesic and anticonvulsant effects in experimental animals. In view of its analgesic and anticonvulsant activity, the JGL extract can be used in painful conditions as well as in seizure disorders.
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