Computed tomographic findings in atrophic rhinitis.

Department of Otolaryngology, University of Toronto, Ontario, Canada.
The Journal of otolaryngology (Impact Factor: 0.5). 01/1992; 20(6):428-32.
Source: PubMed

ABSTRACT Computed tomography (CT) has been used increasingly in the assessment of patients with symptoms of sinonasal disease since the introduction of functional endoscopic surgery for the treatment of chronic sinusitis. The association of sinusitis and atrophic rhinitis will inevitably lead to more frequent imaging of patients with atrophic rhinitis. Correct interpretation of the CT appearances of atrophic rhinitis is important as misinterpretation may have serious implications during sinus surgery. These appearances have not been described previously. We describe and discuss the CT findings in three patients with clinical evidence of atrophic rhinitis.

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    ABSTRACT: Background. The objective of this prospective study was to evaluate the clinical profile, microbiological flora and radiological features in primary atrophic rhinitis patients and to identify their association with the etiology of primary atrophic rhinitis. Study design. Prospective case study. Materials and methods. Patients with primary atrophic rhinitis over a two years period were included in the study. Complete blood count, total protein and microbiological analysis from nasal swab were done to evaluate iron deficiency anemia, nutritional status and identification of the pathogenic bacteria respectively. Radiological evaluation was done to study the radiological features of primary atrophic rhinitis. Observations. Ninety cases of primary atrophic rhinitis were studied. The most common symptom was nasal crusting. Nasal crust, odour and atrophy of mucosa were the most consistent finding. Nasal myiasis was found in 26.6% cases. The nasal mucociliary clearance time was markedly increased. On investigation there were low value of hemoglobin and total protein in 46.6% and 25.5% patients, respectively. Pseudomonas aeruginosa (37%) was the commonest organism isolated from culture. On radiological evaluation evidence of different grade of sinusitis was seen in 87.7% case. Conclusion. The present study suggested that certain bacterial infections, anemia, poor nutrition and hereditary factor may contribute significantly to the etiology of primary atrophic rhinitis.
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    ABSTRACT: Ozena, which is often used interchangeably with atrophic rhinitis or empty nose syndrome, is a progressive and chronically debilitating nasal disease that results in atrophy of the nasal mucosa, nasal crusting, fetor, and destruction of submucosal structures. Although the etiology is not completely understood, infection with Klebsiella ozaenae is widely believed to contribute to the destructive changes. We present a case of a patient with ozena secondary to K. ozaenae with extensive destruction of bony structures of the nasal cavity undergoing elective dacryocystorhinostomy. An extensively thinned skull base secondary to the disease process resulted in an unforeseen complication in which the skull base was entered leading to a cerebrospinal fluid leak. Patients with known history of ozena or atrophic rhinitis often have extensive destruction of the lateral nasal wall and skull base secondary to progression of disease. Submucosal destruction of these bony structures mandates the need for extreme caution when planning on performing endoscopic intervention at or near the skull base. If physical examination or nasal endoscopy is suspicious for atrophic rhinitis or a patient has a known history of infection with K. ozaenae, we recommend preoperative imaging for surgical planning with careful attention to skull base anatomy.
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    ABSTRACT: Objective: In this study, we aimed to examine the ultrastructural characteristics of nasal mucosa in patients with atrophic rhinitis and reported our findings. Methods: The biopsy specimens were obtained from two children and three adult patients, who had some or all of the clas- sical manifestations of atrophic rhinitis. The tissue samples were prepared according to routine histological scanning elec- tron microscopic tissue preparation procedure and examined using scanning electron microscope. The study was carried out in the electron microscopy laboratory of the Anatomy Department of Hacettepe University, Ankara, Turkey, between February 2001 and March 2003. Results: Squamous epithelium showing keratinization was observed in large areas. Additionally, desquamation of the horny cells of the nasal mucosa epithelium was found. The findings obtained in this study were in accordance with preview stud- ies. Besides all these, we also observed accumulation of bacteria, especially the cocci in some focal regions. This accumula- tion of the bacteria may play a very important role in the etiology of the disease. Conclusion: Depending upon to the difficulty of finding patients with atrophic rhinitis, even the few number of cases observed in this study will have an importance for the ultrastructural characteristics of the disease.