Article

Persistence of HIV-1 silent infection in seronegative subjects at high risk.

Institute of Infectious Diseases, Policlinico Umberto I, University of Rome, La Sapienza, Italy.
Journal of Medical Virology (impact factor: 2.82). 10/1991; 35(1):14-8. pp.14-8
Source: PubMed

ABSTRACT Twenty regular sexual partners of HIV-1 infected subjects, without detectable human immunodeficiency virus (HIV-1) antibody and positive for HIV-1 genome by in situ hybridization (ISH), were selected and studied longitudinally for 6-36 months to estimate the duration of silent infection. During the follow-up period, 10 showed atypical Western Blot (WB) patterns. Two seronegative partners seroconverted. Rapid progress to AIDS was observed in 7 seropositive subjects.

0 0
 · 
0 Bookmarks
 · 
14 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

7 seropositive subjects
 
atypical Western Blot
 
detectable human immunodeficiency virus
 
follow-up period
 
HIV-1
 
HIV-1 genome
 
Rapid progress
 
regular sexual partners
 
situ hybridization
 
WB
 

M Pezzella