Article

A model for the propagation and scattering of ultrasound in tissue

Electronics Institute, Technical University of Denmark, Lyngby.
The Journal of the Acoustical Society of America (Impact Factor: 1.56). 02/1991; 89(1):182-90. DOI: 10.1121/1.400497
Source: PubMed

ABSTRACT An inhomogeneous wave equation is derived describing propagation and scattering of ultrasound in an inhomogeneous medium. The scattering term is a function of density and propagation velocity perturbations. The integral solution to the wave equation is combined with a general description of the field from typical transducers used in clinical ultrasound to yield a model for the received pulse-echo pressure field. Analytic expressions are found in the literature for a number of transducers, and any transducer excitation can be incorporated into the model. An example is given for a concave, nonapodized transducer in which the predicted pressure field is compared to a measured field.

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Available from: Jørgen Arendt Jensen, Sep 11, 2014
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    • "Enhanced delivery requires precise control over both ultrasound and microbubble parameters. Although ultrasound parameters are easily controlled and models exist for the propagation of acoustic waves through tissue (Jensen 1991; Zemp et al. 2003), the properties of microbubbles are less predictable. First, the majority of current microbubble production techniques use agitation methods (Klibanov 2002), which generate microbubbles with a wide range of diameters (i.e., polydisperse) "
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