Article

Therapeutic Contact Lenses

International Ophthalmology Clinics 02/1991; 31(2):35-52. DOI: 10.1097/00004397-199103120-00007
Source: PubMed
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    ABSTRACT: PURPOSE: To evaluate the therapeutic effect on amniotic membrane transplantation in symptomatic bullous keratopathy. METHODS: Nine patients with symptomatic bullous keratopathy, candidates or not for penetrating keratoplasty were evaluated before, 1, 3, 6 and 12 months after amniotic membrane transplantation. During each visit, patients have been asked about pain, photophobia, and foreign body sensation and were submitted to complete ophthalmological evaluation, esthesiometry and ultrasound pachymetry. RESULTS: Comparing evaluations performed previously and after the procedure regarding pain, photophobia, foreign body sensation and esthesiometry, there was a statistical significant reduction in symptoms and corneal sensitivity. Medium pachymetry showed an increased thickness soon after the procedure and decreasing between 6 and 12 months. It was observed that after 6 months of follow-up, the transplanted amniotic membrane became partially dissolved in 3 cases (33.3%) and totally dissolved in other 3 cases (33.3%). CONCLUSION: Amniotic membrane transplantation represents an effective alternative for the treatment of symptomatic bullous keratopathy up to 12 months of follow-up.
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    ABSTRACT: OBJETIVO: Avaliar o efeito terapêutico do transplante de membrana amniótica no tratamento da ceratopatia bolhosa. MÉTODOS: Nove pacientes portadores de ceratopatia bolhosa sintomática, com baixa acuidade visual, com e sem indicação de transplante de córnea foram avaliados antes, 1, 3, 6 e 12 meses após transplante de membrana amniótica. Em cada visita, os pacientes foram questionados sobre intensidade da dor, fotofobia, sensação de corpo estranho, e submetidos a exame oftalmológico completo,estesiometria e paquimetria. RESULTADOS: As comparações realizadas entre os valores antes e após o procedimento referentes à dor, fotofobia, sensação de corpo estranho e estesiometria apresentaram diferenças estatisticamente significantes quanto à diminuição desses sintomas e da sensibilidade corneal (p<0,05). A paquimetria apresentou aumento da espessura logo após o procedimento e uma diminuição entre as avaliações de 6 e 12 meses, que foram estatisticamente significantes (p<0,05). Após o sexto mês de seguimento, observou-se reabsorção parcial da membrana amniótica em 3 casos (33,3%) e reabsorção total em outros 3 casos (33,3%). CONCLUSÃO: O transplante de membrana amniótica representa modalidade efetiva no controle dos sintomas da ceratopatia bolhosa por até 12 meses.
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