[Show abstract][Hide abstract] ABSTRACT: This study was designed to evaluate the effect of anterior stromal puncture to treat patients with symptomatic bullous keratopathy.
Fourteen patients with bullous keratopathy who had decreased vision and were or were not awaiting penetrating keratoplasty were evaluated before and 1, 4, 12, and 24 weeks after anterior stromal punctures with a 25-gauge needle. The patients were questioned about pain intensity, foreign-body sensation, and photophobia. Biomicroscopy, esthesiometry, and pachymetry results were evaluated. The results before and after the punctures were compared using the McNemar test, Friedman test, and multiple comparison tests.
The comparisons among before and 1, 4, and 12 weeks after the anterior stromal puncture of pain (p = 0.00000556), photophobia (p = 0.0252), foreign-body sensation (p = 0.0000743), and esthesiometry (p = 0.0243) showed significant statistical differences in terms of decreasing symptoms and corneal sensitivity. The average pachymetry did not show statistical difference among before and 1, 4, 12, and 24 weeks after the procedure (p = 0.956). We did not find important differences in terms of corneal neovascularization.
Anterior stromal puncture is an effective, simple, and low-cost alternative for treating patients with symptomatic bullous keratopathy.
[Show abstract][Hide abstract] ABSTRACT: PURPOSE: To evaluate the therapeutic effect on amniotic membrane transplantation in symptomatic bullous keratopathy. METHODS: Nine patients with symptomatic bullous keratopathy, candidates or not for penetrating keratoplasty were evaluated before, 1, 3, 6 and 12 months after amniotic membrane transplantation. During each visit, patients have been asked about pain, photophobia, and foreign body sensation and were submitted to complete ophthalmological evaluation, esthesiometry and ultrasound pachymetry. RESULTS: Comparing evaluations performed previously and after the procedure regarding pain, photophobia, foreign body sensation and esthesiometry, there was a statistical significant reduction in symptoms and corneal sensitivity. Medium pachymetry showed an increased thickness soon after the procedure and decreasing between 6 and 12 months. It was observed that after 6 months of follow-up, the transplanted amniotic membrane became partially dissolved in 3 cases (33.3%) and totally dissolved in other 3 cases (33.3%). CONCLUSION: Amniotic membrane transplantation represents an effective alternative for the treatment of symptomatic bullous keratopathy up to 12 months of follow-up.
Arquivos Brasileiros de Oftalmologia 12/2002; 66(2):121-124. · 0.42 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: OBJETIVO: Avaliar o efeito terapêutico do transplante de membrana amniótica no tratamento da ceratopatia bolhosa. MÉTODOS: Nove pacientes portadores de ceratopatia bolhosa sintomática, com baixa acuidade visual, com e sem indicação de transplante de córnea foram avaliados antes, 1, 3, 6 e 12 meses após transplante de membrana amniótica. Em cada visita, os pacientes foram questionados sobre intensidade da dor, fotofobia, sensação de corpo estranho, e submetidos a exame oftalmológico completo,estesiometria e paquimetria. RESULTADOS: As comparações realizadas entre os valores antes e após o procedimento referentes à dor, fotofobia, sensação de corpo estranho e estesiometria apresentaram diferenças estatisticamente significantes quanto à diminuição desses sintomas e da sensibilidade corneal (p<0,05). A paquimetria apresentou aumento da espessura logo após o procedimento e uma diminuição entre as avaliações de 6 e 12 meses, que foram estatisticamente significantes (p<0,05). Após o sexto mês de seguimento, observou-se reabsorção parcial da membrana amniótica em 3 casos (33,3%) e reabsorção total em outros 3 casos (33,3%). CONCLUSÃO: O transplante de membrana amniótica representa modalidade efetiva no controle dos sintomas da ceratopatia bolhosa por até 12 meses.
Arquivos Brasileiros de Oftalmologia 01/2003; DOI:10.1590/S0004-27492003000200002 · 0.42 Impact Factor
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