A case of infiltrating lipomatosis with diffuse, symmetrical distribution.

Department of Internal Medicine, Cukurova University Medical School, Adana, Turkey.
The British journal of clinical practice 01/1991; 44(12):728-30.
Source: PubMed


Infiltrating lipomatosis represents a distinct clinicopathological entity characterised by collections of non-encapsulated, mature lipocytes that infiltrate local tissues. The lesions are usually first observed during the first three decades of life, but congenital types exist. Although a predilection for the lower extremity exists in approximately 80% of patients, they can affect a multitude of anatomic sites. Infiltrating lipomatosis of the face, head and neck, upper and lower extremities, trunk and abdominal cavity and pelvis have all been reported. The patient presented here had symmetrical, diffuse infiltrating lipomatosis involving almost the whole body, sparing only the head, neck, fingers and toes.

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    ABSTRACT: The literature is in agreement in the management of diffuse lipomatosis. Briefly, combined lipectomy and liposuction is the treatment of choice. The management of diffuse lipomatosis shows great similarity to the management described for lymphedema of the lower extremity. The lipomatosis should be meticulously debulked to preserve the existing muscular and neurovascular structures that are encased by the lipomatosis. In diffuse lipomatosis, radical resection with liposuction may lead to significant cosmetic and functional improvement with the relief of tumor bulk. Because local recurrence after surgical removal may occur, long-term follow-up of these patients is recommended.
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