Mosaic acral keratosis
Department of Dermatology, Kalafong Hospital, Pretoria, Republic of South Africa.Clinical and Experimental Dermatology (Impact Factor: 1.09). 10/1990; 15(5):361-2. DOI: 10.1111/j.1365-2230.1990.tb02114.x
We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one patient also had keratotic papules on the hands and hyperkeratotic plaques over the knees. The differential diagnosis of acral keratoses, including several recently described forms, is briefly discussed.
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ABSTRACT: Children living on plantations in inland districts of the southeastern part of Sri Lanka frequently develop a skin condition on the legs described as mosaic skin or xeroderma. This condition is characterized by atrophic, dry, shining and scaly skin. The etiology is unknown. A food frequency survey indicated a low energy intake, a diet with a low fat content, and anthropometric data have shown a high prevalence of malnutrition within this group. The skin condition brought attention to a possible deficiency of essential nutrients, especially essential fatty acids. In order to investigate the possible association with a deficiency of essential fatty acids, blood samples were collected from both children having signs of xeroderma and controls. The total amount of phospholipids was low, but the fatty acid profile of this lipid class was similar to the controls. A vitamin A deficiency was indicated by low levels of its transport proteins. A multifactorial etiology where vitamin A deficiency may play a role is discussed.Annals of Nutrition and Metabolism 02/1995; 39(1):9-15. DOI:10.1159/000177837 · 2.62 Impact Factor
- International Journal of Dermatology 07/2000; 39(6):424-32. DOI:10.1046/j.1365-4362.2000.00940.x · 1.31 Impact Factor
Article: Acrokeratoelastoidosis[Show abstract] [Hide abstract]
ABSTRACT: Acrokeratoelastoidosis of Costa is a rare papular palmoplantar keratosis characterized by small round-oval to rhomboid-shaped, yellowish papules most commonly localized to the palmar surface of the hands and sometimes also found on plantar surfaces of the feet. Both autosomal dominant and sporadic forms of the disease have been reported. Histologically acrokeratoelastoidosis is marked by hyperkeratosis and epidermal hypertrophy. Specific stains for elastic tissue reveal characteristic fragmentation and rarefaction of elastic fibers. We report a sporadic case of acrokeratoelastoidosis in a 13-year-old girl and review the etiology, differential diagnosis, and treatment of this disorder.Pediatric Dermatology 07/2002; 19(4):320-2. DOI:10.1046/j.1525-1470.2002.00091.x · 1.02 Impact Factor
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