Mosaic acral keratosis
Department of Dermatology, Kalafong Hospital, Pretoria, Republic of South Africa.Clinical and Experimental Dermatology (Impact Factor: 1.09). 10/1990; 15(5):361-2. DOI: 10.1111/j.1365-2230.1990.tb02114.x
We describe two patients with acral keratosis with a striking mosaic or jigsaw-puzzle pattern of keratotic papules on the dorsal aspects of the feet and adjacent parts of the legs. Both patients also showed mild diffuse palmoplantar keratosis and clavus-like lesions over the interphalangeal joints of the toes; one patient also had keratotic papules on the hands and hyperkeratotic plaques over the knees. The differential diagnosis of acral keratoses, including several recently described forms, is briefly discussed.
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ABSTRACT: Several entities, quite often similar, share keratotic papules, usually crateriform, along the border of the hands and feet as a common clinical finding. These conditions are acrokeratoelastoidosis of Costa, focal acral hyperkeratosis, acrokeratoelastoidosis of Matthews and Harman, mosaic acral keratosis, hereditary papulotranslucent acrokeratoderma, acrokeratoderma hereditarium punctatum, degenerative collagenous plaques of the hands, keratoelastoidosis marginalis and digital papular calcinosis. We describe two further cases of focal acral hyperkeratosis in two Caucasian women, review the clinical and histological features of the related conditions and suggest that some are variants of the same entity. We propose the simplified concept of marginal papular acrokeratodermas that may be divided into (1) the hereditary type (subdivided into that with and without elastorrhexis) and (2) the acquired type.Dermatology 02/1994; 188(1):28-31. DOI:10.1159/000247081 · 1.57 Impact Factor
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ABSTRACT: Children living on plantations in inland districts of the southeastern part of Sri Lanka frequently develop a skin condition on the legs described as mosaic skin or xeroderma. This condition is characterized by atrophic, dry, shining and scaly skin. The etiology is unknown. A food frequency survey indicated a low energy intake, a diet with a low fat content, and anthropometric data have shown a high prevalence of malnutrition within this group. The skin condition brought attention to a possible deficiency of essential nutrients, especially essential fatty acids. In order to investigate the possible association with a deficiency of essential fatty acids, blood samples were collected from both children having signs of xeroderma and controls. The total amount of phospholipids was low, but the fatty acid profile of this lipid class was similar to the controls. A vitamin A deficiency was indicated by low levels of its transport proteins. A multifactorial etiology where vitamin A deficiency may play a role is discussed.Annals of Nutrition and Metabolism 02/1995; 39(1):9-15. DOI:10.1159/000177837 · 2.62 Impact Factor
- Dermatology 02/1995; 190(2):178-9. DOI:10.1159/000246677 · 1.57 Impact Factor
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