Article

Effects of heparin versus saline solution on intermittent infusion device irrigation.

Shawnee Mission Medical Center, Mission, KS 66201.
Heart and Lung The Journal of Acute and Critical Care (Impact Factor: 1.4). 12/1990; 19(6):608-12.
Source: PubMed

ABSTRACT The purpose of this study was to compare the effectiveness of 1 ml of 0.9% sodium chloride with 10 units of heparin in 1 ml sodium chloride solution, both containing benzyl alcohol, in maintaining patency and reducing the incidence of phlebitis in patients with intermittent infusion devices. The subjects (N = 32) were randomly assigned in a double-blind experimental design. Repeated-measures analysis of variance revealed no significant difference between the groups in phlebitis or patency variables. The results from this controlled study would suggest that 0.9% sodium chloride is as effective as 10 units of heparin in sodium chloride solution in maintaining intermittent infusion device patency and preventing phlebitis.

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