HLA typing in actinic prurigo.

Department of Medicine, University of Saskatchewan, Saskatoon, Canada.
Journal of the American Academy of Dermatology (Impact Factor: 5). 07/1990; 22(6 Pt 1):1019-23.
Source: PubMed

ABSTRACT Thirty-two actinic prurigo patients of Cree ancestry underwent human lymphocyte antigen (HLA) typing and were compared with 32 control subjects of Cree ancestry. We found a significantly increased frequency of HLA-A24 and Cw4 antigens and a significant decrease in the frequency of the A3 antigen in actinic prurigo patients. These HLA associations may be helpful in determining whether actinic prurigo is a distinct disease or a variant of polymorphous light eruption.