We assessed 96 patients with obsessive-compulsive disorder for DSM-III personality disorder diagnoses with a standardized interview instrument (Structured Interview for the DSM-III Personality Disorders). Fifty patients (52%) met criteria for at least one personality disorder, with mixed, dependent, and histrionic personality disorders most frequently diagnosed. Compulsive personality disorder was diagnosed in only 6 patients (6%), 5 of whom had had onset of obsessive-compulsive symptoms before the age of 10 years, indicating that DSM-III compulsive personality disorder is not invariably a premorbid condition for the development of obsessive-compulsive disorder. Schizotypal personality disorder, at 5%, was found to be less common than in past samples, reflecting differences in either assessment methods or sampling.
"However, when examining the association between OCD and OCPD, our results did not confirm a specific relationship given that no significant differences were found between clinical groups. Results in this study fail to demonstrate the alleged continuum between both disorders [32, 35], contradicting recent studies that have suggested comorbidity between OCD and OCPD as a distinct subtype of OCD and describe its characteristics [36, 37]. "
[Show abstract][Hide abstract] ABSTRACT: Objective
. The purpose of this paper is to provide evidence for the relationship between personality disorders (PDs), obsessive compulsive disorder (OCD), and other anxiety disorders different from OCD (non-OCD) symptomatology.
. The sample consisted of a group of 122 individuals divided into three groups (41 OCD; 40 non-OCD, and 41 controls) matched by sex, age, and educational level. All the individuals answered the IPDE questionnaire and were evaluated by means of the SCID-I and SCID-II interviews.
. Patients with OCD and non-OCD present a higher presence of PD. There was an increase in cluster C diagnoses in both groups, with no statistically significant differences between them.
. Presenting anxiety disorder seems to cause a specific vulnerability for PD. Most of the PDs that were presented belonged to cluster C. Obsessive Compulsive Personality Disorder (OCPD) is the most common among OCD. However, it does not occur more frequently among OCD patients than among other anxious patients, which does not confirm the continuum between obsessive personality and OCD. Implications for categorical and dimensional diagnoses are discussed.
The Scientific World Journal 12/2013; 2013(2):856846. DOI:10.1155/2013/856846 · 1.73 Impact Factor
"Inoltre, i pazienti con DOC che successivamente sviluppano un disturbo bipolare manifestano anche tassi più alti di disturbi di panico/agorafobia, disturbi da uso di sostanze e, nei bambini, disturbi della condotta e disturbo da deficit di attenzione/iperattività (Attention-Deficit/Hyperactivity Disorder, ADHD) [16—18,20,22]. Per quanto concerne la comorbilità di Asse II, i risultati presentati in letteratura sono piuttosto scarsi e contraddittori  : in un precedente studio condotto presso il nostro Servizio su un campione di pazienti con DOC era emerso, nei soggetti con disturbo bipolare in comorbilità, un'associazione con disturbo antisociale e narcisistico di personalità . Lo scopo di questo studio è mettere in evidenza, in un'ampia casistica di pazienti affetti da DOC, le differenze sociodemografiche e cliniche che emergono tra i pazienti con e senza disturbo bipolare associato. "
[Show abstract][Hide abstract] ABSTRACT: IntroductionThe onset of bipolar symptoms in patients with obsessive-compulsive disorders (OCD) is a common problem with important prognostic and therapeutic implications. Rates of comorbidity between the two disorders run as high as 30%. The aim of the present study was to explore socio-demographic and clinical differences between OCD patients with and without bipolar disorders to identify predictive factors that can guide treatment choices.
Quaderni Italiani di Psychiatria 09/2011; 30(2):75-82. DOI:10.1016/j.quip.2011.04.002
"Several studies have documented a high prevalence of obsessive– compulsive personality disorder (OCPD) in obsessive–compulsive disorder (OCD). Clinical studies using the DSM-III and DSM-III-R criteria for OCPD have found OCPD comorbidity rates in OCD ranging between 6 and 31% (Baer et al., 1990; Diaferia et al., 1997; Mancebo et al., 2005). More recent clinical studies using DSM-IV criteria have found OCPD comorbidity rates ranging from 23% to 32% (Albert et al., 2004; Coles et al., 2008; Pinto et al., 2006; Samuels et al., 2000). "
[Show abstract][Hide abstract] ABSTRACT: Comorbid obsessive-compulsive personality disorder (OCPD) is well-described in obsessive-compulsive disorder (OCD). It remains unclear, however, whether OCPD in OCD represents a distinct subtype of OCD or whether it is simply a marker of severity in OCD.
The aim of this study was to compare a large sample of OCD subjects (n=403) with and without OCPD on a range of demographic, clinical and genetic characteristics to evaluate whether comorbid OCPD in OCD represents a distinct subtype of OCD, or is a marker of severity.
Our findings suggest that OCD with and without OCPD are similar in terms of gender distribution and age at onset of OC symptoms. Compared to OCD-OCPD (n=267, 66%), those with OCD+OCPD (n=136, 34%) are more likely to present with the OC symptom dimensions which reflect the diagnostic criteria for OCPD (e.g., hoarding), and have significantly greater OCD severity, comorbidity, functional impairment, and poorer insight. Furthermore there are no differences in distribution of gene variants, or response to treatment in the two groups.
The majority of our findings suggest that in OCD, patients with OCPD do not have a highly distinctive phenomenological or genetic profile, but rather that OCPD represents a marker of severity.
Progress in Neuro-Psychopharmacology and Biological Psychiatry 03/2011; 35(4):1087-92. DOI:10.1016/j.pnpbp.2011.03.006 · 3.69 Impact Factor
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