Article

Lack of effect of alpha-tocopherol and ascorbic acid on the response of some physiological variables to immobilization stress in rat.

Departamento de Biología Celular y Fisiología, Facultad de Ciencias, Bellaterra, Barcelona, Spain.
Revista española de fisiología 10/1989; 45(3):277-80.
Source: PubMed

ABSTRACT The effect of alpha-tocopherol or ascorbic acid jointly and separately on the seric levels of adrenocorticotropin (ACTH) and corticosterone has been studied. ACTH response to stress is similar in all groups, whereas the corticosterone response is higher in the animals treated with alpha-tocopherol. Neither lactate response nor gastric ulceration caused by stress was influenced by the administration of alpha-tocopherol and/or ascorbic acid. These results suggest that free radicals might not be implicated in the control of the physiological response to stress.

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Keywords

ACTH
 
ACTH response
 
alpha-tocopherol
 
ascorbic acid
 
corticosterone response
 
free radicals
 
gastric ulceration
 
lactate response
 
physiological response
 
seric levels