Association between low gynaecological age and preterm birth

Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Camden 08103.
Paediatric and Perinatal Epidemiology (Impact Factor: 3.13). 11/1989; 3(4):357-66.
Source: PubMed


Low gynaecological age, defined as conception within 2 completed years of menarche, was examined for its association with preterm birth, using data from a geographically based cohort of over 1700 young primigravidae aged 18 or younger at start of prenatal care. After stratifying by chronological age and controlling for confounding variables, low gynaecological age was associated with almost double the risk of preterm delivery whether estimated from the mother's last menstrual period (adjusted odds ratio (AOR) = 1.77, 95% CI 1.19-2.64) or using the obstetric estimate of gestation (AOR = 2.10, 95% CI 1.36-3.25). Low gynaecological age was also associated with an increase in risk of low birthweight (LBW) (AOR = 1.70, 95% CI 1.01-2.88), but not of small-for-gestational-age babies (AOR = 0.94, 95% CI 0.49-1.81). Thus low gynaecological age may be an important addition to assessment systems to detect women at risk of preterm labour and delivery.

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Available from: Mary L Hediger, Feb 24, 2015
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    • "It also represents a transition from the state of socio-economic dependence to one of relative (1, 2). Adolescent pregnancy is defined as gestation in women before having reached the full somatic development (3). The percentage of childbearing adolescent women highly varies by regionally depending on cultural, religious, political, economic and other factors (4). "
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    ABSTRACT: Young maternal age at delivery has been proposed as risk factor for adverse pregnancy outcome, it occurs in all races, faiths, socioeconomic statuses, and regions. Teenage pregnancy can have serious physical consequences and teenage mothers are likely to be unmarried, poor and remain uneducated. The objective of the study was to evaluate risk factors associated with teenage pregnancy and compare the obstetric and fetal outcome to older parturient. This is a retrospective study performed over a period of 4 Years (January 1, 2007 to December 31, 2010) in Niger Delta University Teaching Hospital Bayelsa State, Nigeria where data was retrieved from the hospital records. All teenage mothers (aged 13-19) who had delivery within the period were compared with 180 randomly selected deliveries in the older age group (20-32 years) over the same period. Variables of interest were the demographic characteristics of the women, their obstetric complications and the outcome. There were a total of 1341 deliveries during the study period, out which 83(6.2%) were teenagers. Teenage mothers were significantly more likely to be unbooked, (p = 0.000) Unmarried, (χ=26.2; p = 0.000) had significantly more preterm labor, (P=0.000) and Caesarean sections (P= 0.014). However, there was no difference in both the perinatal and maternal mortality rates between the two groups. Teenage pregnancy in the Niger Delta is concentrated among women with less formal education, who are unemployed, unmarried and with inadequate antenatal care and obstetric risks for poor pregnancy outcome. The provision an appropriate contraceptive method and to look with priority after any pregnancy occurring among this age group cannot be overemphasized.
    Ethiopian journal of health sciences 03/2012; 22(1):45-50.
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    • "Adolescent pregnancy is defined as gestation of women before having reached the full somatic development [10].The percentage of childbearing adolescent women is regionally highly variable depending on cultural, religious, political, economic and other factors [11]. Early pregnancy has been discussed as an independent risk factor for adverse pregnancy outcome. "
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    ABSTRACT: Sub-Saharan Africa has the highest rates of maternal and neonatal mortality worldwide. Young maternal age at delivery has been proposed as risk factor for adverse pregnancy outcome, yet there is insufficient data from Sub-Saharan Africa. The present study aimed to investigate the influence of maternal adolescence on pregnancy outcomes in the Central African country Gabon. Data on maternal age, parity, birth weight, gestational age, maternal Plasmodium falciparum infection, use of bednets, and intake of intermittent preventive treatment of malaria in pregnancy were collected in a cross-sectional survey in 775 women giving birth in three mother-child health centers in Gabon. Adolescent women (≤16 years of age) had a significantly increased risk to deliver a baby with low birth weight in univariable analysis (22.8%, 13/57, vs. 9.3%, 67/718, OR: 2.9, 95% CI: 1.5-5.6) and young maternal age showed a statistically significant association with the risk for low birth weight in multivariable regression analysis after correction for established risk factors (OR: 2.7; 95% CI: 1.1-6.5). In further analysis adolescent women were shown to attend significantly less antenatal care visits than adult mothers (3.3±1.9 versus 4.4±1.9 mean visits, p<0.01, n = 356) and this difference accounted at least for part of the excess risk for low birth weight in adolescents. Our data demonstrate the importance of adolescent age as risk factor for adverse pregnancy outcome. Antenatal care programs specifically tailored for the needs of adolescents may be necessary to improve the frequency of antenatal care visits and pregnancy outcomes in this risk group in Central Africa.
    PLoS ONE 12/2010; 5(12):e14367. DOI:10.1371/journal.pone.0014367 · 3.23 Impact Factor
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    • "International studies from low-income settings report low maternal age as a risk factor for preterm delivery and consequently also for low birth weight [26] [27] [28] [29]. Other studies have indicated that women below 16 with low gestational age (GA) run a higher risk for both preterm delivery and LBW infant as compared to adult women [30]. Nonutilization of antenatal care (ANC), rather than biological factors such as low GA, has further been identified as a risk factor for stillbirth , preterm delivery and LBW infant [22] among pregnant adolescents [8]. "
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    ABSTRACT: To describe birth rates and pregnancy outcomes, specifically stillbirth, preterm delivery and low birth weight (LBW) in relation to socio-demographic characteristics, among adolescent women in a rural district in northern Vietnam. Within an epidemiological field laboratory, quarterly surveillance of 7767 adolescent women in the ages 15-19 during the period January 1999 to December 2005 was conducted. Birth rates were calculated and pregnancy outcomes were described in relation to background factors. A total of 1021 pregnancies were reported by 926 adolescent women during the period of whom 17% were below 18 years. The estimated adolescent birth rate during 1999-2005 was 27/1000 women-years. The incidence of stillbirth among all births was 19/1000 births. These were more likely to be delivered preterm. The incidence of preterm deliveries and LBW infants was 193 and 75 per 1000 live births, respectively. There were no differences in socio-demographic background for stillbirth, preterm delivery or LBW. Adolescent birth rates were similar to those found in the recent Vietnamese DHS and considerably lower than the average for South-East Asia. Higher rates of stillbirth and preterm delivery were found than those previously reported for Vietnam, indicating the need for careful monitoring of adolescent pregnancies and their infants. Further research is needed to explore if and how much socio-demographic variables influence pregnancy outcome, comparing more differentiated groups, as a basis for interventions to assure access to adequate reproductive health care services for all women.
    Sexual & reproductive healthcare: official journal of the Swedish Association of Midwives 02/2010; 1(1):15-9. DOI:10.1016/j.srhc.2009.09.002 · 1.25 Impact Factor
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