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[Esophageal variceal pressure by endoscopic pneumatic pressure sensor in patients with liver cirrhosis].

ABSTRACT The esophageal variceal pressure was determined by endoscopic pneumatic pressure sensor method in patients with liver cirrhosis, complicating esophageal varices. The variceal pressure by this method was significantly correlated with percutaneous transhepatic portal venous pressure. The variceal pressure was related with endoscopic findings of varices, especially of red-color sign, form and location. The variceal pressure below 200 mmH2O showed negligible risk of variceal bleeding, and the pressure over 350 mmH2O was associated with high risk of variceal bleeding. These results indicate that esophageal variceal pressure by this method may provide useful informations in natural history of esophageal varices.

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    ABSTRACT: Intravascular esophageal variceal pressure (IEVP) was measured using a flexible indwelling needle and compared with wedged hepatic venous pressure (WHVP) in 38 patients with liver cirrhosis. There was a high correlation between IEVP and WHVP; the former was lower than the latter, indicating the presence of a pressure gradient. Bleeders with a history of esophageal variceal rupture showed higher IEVP value than non-bleeders without a history of rupture, even though no difference in WHVP was observed. IEVP in the post-endoscopic injection sclerotherapy (EIS) group, even in those with endoscopic findings of large varices, was lower than that in the untreated groups. These results suggest that IEVP is a factor in the hemodynamics of patients with portal hypertension and that its measurement may be helpful in elucidating the pathophysiology of esophageal varices.
    Journal of Gastroenterology 28(5):631-637. · 3.79 Impact Factor