Article

Parvovirus infection after renal transplant.

The Lancet (Impact Factor: 45.22). 12/1986; 2(8517):1226-7. DOI: 10.1016/S0140-6736(86)92245-2
Source: PubMed
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    ABSTRACT: Als bekannte Manifestation einer Parvovirus B19-Infektion wird am häufigsten das meist im Kindesalter auftretende Erythema infectiosum („Ringelröteln“) mit einem schmetterlingsförmigen Exanthem im Gesicht und girlandenförmiger Ausbreitung auf die Extremitäten beschrieben. Diese Hautveränderungen sind oft mit Krankheitsgefühl, Fieber und Arthralgien verbunden. Darüber hinaus kann das Virus bei Patienten mit chronischen hämolytischen Anämien schwere aplastische Krisen und in der Schwangerschaft einen letalen Hydrops fetalis verursachen. Es werden drei Patientinnen mit einer Parvovirus B19-Infektion vorgestellt. Die dermatologische Symptomatik entsprach einem z.T. bullös – z.T. papulo – makulösem Exanthem, einem Erythema exsudativum multiforme oder einer Purpura. Die Parvovirus B19-Infektion wurde serologisch und mit der Polymerase-Kettenreaktions-Technik verifiziert. Im Rahmen der oft schwierigen Differentialdiagnose akut aufgetretener Exantheme ist den viralen Infektionen zunehmend Aufmerksamkeit zu widmen. Infections with parvovirus B19 are often characterized by the well-known erythema infectiosum, usually accompanied by fever and arthralgia. Furthermore the virus may cause a lethal hydrops fetalis during the pregnancy or a severe aplastic crisis in patients suffer from chronic hemolytic anemia. We present three patients infected by parvovirus B19. Whose skin lesions included a non-specific exanthem, erythema multiforme, and purpura. The virus infection was confirmed both by serology and PCR identification. In conclusion the diagnosis of acute exanthems should include the search for virus infections.
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